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Role of Intra-Abdominal Pressure as a Prognostic Marker and Its Correlation with APACHE II and SOFA Scores in Patients of Acute Pancreatitis

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Abstract

Intra-abdominal hypertension (IAH) is a known but neglected complication in acute pancreatitis. The present study was conducted to establish the role of intra-abdominal pressure (IAP) as a prognostic marker in patients with acute pancreatitis and also to correlate IAP with APACHE II and SOFA scores. A prospective observational single-center cohort study was conducted on adult patients diagnosed with acute pancreatitis. Intra-abdominal pressure was measured through a transurethral Foley’s bladder catheter. APACHE II and SOFA scores were calculated at the time of admission (day 1). APACHE II score was reevaluated on day 3 and 5. SOFA score was reevaluated everyday till day 5. APACHE II score, SOFA score, and IAP at admission were significantly higher among non survivors when compared to survivors. There was significant correlation of IAP with APACHE II and SOFA scores. APACHE II and SOFA scores at cut-off values of 12 and 6 predicted IAP of > 12 (mm of Hg) with reasonable sensitivity and specificity. IAP could be used as a reliable negative prognostic marker in acute pancreatitis. APACHE II and SOFA scores could be used to predict intra-abdominal hypertension in patients of acute pancreatitis.

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Authors and Affiliations

  1. Department of Surgery, Ward 17, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, Pin-110001, India

    Arun Kumar Gupta, Ekta Yadav, Nikhil Gupta, Raghav Yelamanchi, Lalit Kumar Bansal & C. K. Durga

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  1. Arun Kumar Gupta
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  2. Ekta Yadav
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  3. Nikhil Gupta
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  4. Raghav Yelamanchi
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  5. Lalit Kumar Bansal
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  6. C. K. Durga
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Corresponding author

Correspondence to Raghav Yelamanchi.

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Ethical Approval

This study was performed in line with the principles of the Declaration of Helsinki 1975 revised in 2013. Approval was granted by the Ethics Committee of PGIMER/RMLH with approval number T.P(MD/MS) (45/2015)/IEC/PGIMER/RML/5016.

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Authorship: All authors of this manuscript confirm that they qualify for (co-)authorship, according to the “Uniform Requirements for Manuscripts” published in the guidelines of the “International Committee of Medical Journal Editors” in 1988

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Gupta, A.K., Yadav, E., Gupta, N. et al. Role of Intra-Abdominal Pressure as a Prognostic Marker and Its Correlation with APACHE II and SOFA Scores in Patients of Acute Pancreatitis. Indian J Surg 84 (Suppl 2), 485–491 (2022). https://doi.org/10.1007/s12262-021-02854-7

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  • DOI: https://doi.org/10.1007/s12262-021-02854-7

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