Abstract
Rectal cancer presenting with intestinal obstruction has historically been associated with poor outcomes. However, most of these studies were published before the neoadjuvant chemoradiation era. We intended to look for the outcomes of patients with rectal cancer presenting with and without luminal occlusion. One hundred eighty-nine consecutive patients, compliant with the treatment protocol from January 2013 to May 2014 were included in the study. They were classified as lumen-occluding or non-lumen-occluding based on colonoscopy, and outcomes were compared in the 2 groups. The two groups had similar demographic profiles. Median follow-up time of the study cohort was 5 years. The 5-year overall survival was 72.2% and 54.8% in the lumen non-occluding and lumen-occluding group, respectively. This difference was not statistically significant (p–0.34). However, 5-year disease-free survival was 65.1% and 39.9% in the non-occluding group and lumen-occluding group, respectively (p = 0.02). This difference in disease-free survival was not significant on multivariate analysis (p–0.07). Lumen-occluding growths on colonoscopy are not associated with poor outcomes in today’s era.
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Impact of lumen occlusion/obstruction is not studied/reported in post NACTRT era; our study is the first to look into this issue.
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Shinde, R.S., Gupta, A., Patil, P. et al. Impact of Lumen Occlusion on Outcomes in Locally Advanced Rectal Adenocarcinoma. Indian J Surg 83, 1401–1406 (2021). https://doi.org/10.1007/s12262-020-02678-x
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DOI: https://doi.org/10.1007/s12262-020-02678-x