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SELSI Consensus Statement for Safe Cholecystectomy—Prevention and Management of Bile Duct Injury—Part B

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Abstract

Cholecystectomy is one of the commonest general surgical procedures performed all over India. The risk of bile duct injury (BDI) during laparoscopic cholecystectomy is two to three times higher than during open cholecystectomy. The worldwide incidence of bile duct injury is 0.5% or 1 in 200 cases. BDI and its consequences result in significant morbidity and may even cause mortality. BDI increases the cost of treatment and is a common reason for a medicolegal suit against the surgeons. To minimize the incidence of BDI and to manage it timely and appropriately, a set of guidelines was deemed necessary by a group of senior surgeons during a Society of Endoscopic and Laparoscopic Surgeons of India (SELSI) meeting in 2016. Guidelines for “Safe Laparoscopic Cholecystectomy” and bile duct injury management formulated by other international societies are already available. The applicability of these guidelines to Indian subjects especially in small peripheral centers was limited. Hence, a decision was taken to form a set of guidelines for general surgeons with basic laparoscopic skills with little or no advanced laparoscopic skills. Those working in a solo practice, nursing homes, and small private hospitals at talukas or districts should have “Safe Cholecystectomy” guidelines and management of BDI suitable to their situation. These guidelines were formed after three consensus meetings and have been approved by a SELSI Expert Group.

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Abbreviations

AIDS :

Acquired immune deficiency syndrome

ALP :

Alkaline phosphatase

ASA :

American Society of Anesthesiologists

BDI :

Bile duct injury

BMI :

Body mass index

CBD :

Common bile duct

CECT :

Contrast enhanced computerized tomography

CHA :

Chronic hemolytic anemia

CHD :

Common hepatic duct

COPD :

Chronic obstructive pulmonary disease

CVS :

Critical view of safety

DLC :

Delayed laparoscopic cholecystectomy

EAES :

European Association of Endoscopic Surgeons

EBF :

External biliary fistula

ELC :

Early laparoscopic cholecystectomy

ERCP :

Endoscopic retrograde cholangio-pancreatography

ESE :

Endoscopic papillotomy and stone extraction

FNAC :

Fine needle aspiration cytology

GB :

Gallbladder

HIDA :

Hepatobiliary iminodiacetic acid scan

HIV :

Human immune deficiency virus

IHBRD :

Intrahepatic biliary radical dilatation

IOC :

Intraoperative cholangiogram

IRCAD :

L’Institut de Recherchecontre les Cancers de l'AppareilDigestif

KFT :

Kidney function test

LC :

Laparoscopic cholecystectomy

LCBDE :

Laparoscopic common bile duct exploration

LFT :

Liver function test

LMWH :

Low molecular weight heparin

LOE :

Level of evidence

MRC :

Magnetic resonance cholangiogram

MRCP :

Magnetic resonance cholangio-pancreatography

MS :

Mirizzi's syndrome

OC :

Open cholecystectomy

OHA :

Oral hypoglycemic agents

SAGES :

Society of American Gastrointestinal and Endoscopic Surgeons

SELSI :

Society of Endoscopic and Laparoscopic Surgeons of India

SCD :

Sickle cell disease

TLC :

Total leucocyte count

WBC :

White blood cell

USG :

Ultrasonography

References

  1. Shekelle PG, Woolf SH, Eccles M, Grimshaw J (1999) Developing clinical guidelines. West J Med 170:348–351

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Deziel DJ, Millikan KW, Economou SG et al (1993) Complications of laparoscopic cholecystectomy: a national survey of 4,292 hospitals and an analysis of 77,604 cases. Am J Surg 165:9–14

    Article  CAS  Google Scholar 

  3. Shea JA, Healey MJ, Berlin JA et al (1996) Mortality and complications associated with laparoscopic cholecystectomy. A meta-analysis. Ann Surg 224:609–620

    Article  CAS  Google Scholar 

  4. Terho PM, Leppäniemi AK, Mentula PJ (2016) Laparoscopic cholecystectomy for acute calculous cholecystitis: a retrospective study assessing risk factors for conversion and complications. World J Emerg Surg WJES 11:54–59. https://doi.org/10.1186/s13017-016-0111-4

    Article  PubMed  Google Scholar 

  5. Mangieri CW, Hendren BP, Strode MA, Bandera BC, Faler BJ (2019) Bile duct injuries (BDI) in the advanced laparoscopic cholecystectomy era. Surg Endosc 33:724–730. https://doi.org/10.1007/s00464-018-6333-7

    Article  PubMed  Google Scholar 

  6. Fong ZV, Pitt HA, Strasberg SM et al (2018) Diminished survival in patients with bile leak and ductal injury: management strategy and outcomes. J Am Coll Surg 226:568–576.e1. https://doi.org/10.1016/j.jamcollsurg.2017.12.023

  7. Törnqvist B, Strömberg C, Persson G, Nilsson M (2012) Effect of intended intraoperative cholangiography and early detection of bile duct injury on survival after cholecystectomy: population based cohort study. The BMJ 345:. https://doi.org/10.1136/bmj.e6457

  8. Kapoor VK (2016) Medico-legal aspects of bile duct injury. J Minimal Access Surg 12:1–3. https://doi.org/10.4103/0972-9941.169995

    Article  Google Scholar 

  9. Pekolj J, Alvarez FA, Palavecino M et al (2013) Intraoperative management and repair of bile duct injuries sustained during 10,123 laparoscopic cholecystectomies in a high-volume referral center. J Am Coll Surg 216:894–901. https://doi.org/10.1016/j.jamcollsurg.2013.01.051

    Article  PubMed  Google Scholar 

  10. Rystedt JML, Montgomery AK (2016) Quality-of-life after bile duct injury: intraoperative detection is crucial. A national case-control study HPB 18:1010–1016. https://doi.org/10.1016/j.hpb.2016.09.003

    Article  PubMed  Google Scholar 

  11. Alvarez FA, de Santibañes M, Palavecino M et al (2014) Impact of routine intraoperative cholangiography during laparoscopic cholecystectomy on bile duct injury. Br J Surg 101:677–684. https://doi.org/10.1002/bjs.9486

    Article  CAS  PubMed  Google Scholar 

  12. Fischer CP, Fahy BN, Aloia TA et al (2009) Timing of referral impacts surgical outcomes in patients undergoing repair of bile duct injuries. HPB 11:32–37. https://doi.org/10.1111/j.1477-2574.2008.00002.x

    Article  PubMed  PubMed Central  Google Scholar 

  13. Rogers EA, Tang S, Porter J, Ahmed N (2011) Suspected bile duct injuries and appropriate early referral can reduce chances of litigation. J Miss State Med Assoc 52:275–277

    PubMed  Google Scholar 

  14. Karvonen J, Gullichsen R, Laine S et al (2007) Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution. Surg Endosc 21:1069–1073. https://doi.org/10.1007/s00464-007-9316-7

    Article  PubMed  Google Scholar 

  15. Joshi RM, Shetty TS, Singh R et al (2008) Biliary complications of cholecystectomy. Int Surg 93:251–256

    PubMed  Google Scholar 

  16. Sikora SS, Kumar A, Das NR et al (2001) Laparoscopic bile duct injuries: spectrum at a tertiary-care center. J Laparoendosc Adv Surg Tech A 11:63–68. https://doi.org/10.1089/109264201750162239

    Article  CAS  PubMed  Google Scholar 

  17. Slater K, Strong RW, Wall DR, Lynch SV (2002) Iatrogenic bile duct injury: the scourge of laparoscopic cholecystectomy. ANZ J Surg 72:83–88

    Article  CAS  Google Scholar 

  18. Luo D, Chen X-R, Li S-H et al (2002) Non-image diagnosis of bile duct injury during laparoscopic cholecystectomy. Hepatobiliary Pancreat Dis Int HBPD INT 1:106–110

    PubMed  Google Scholar 

  19. Xu XD, Zhang YC, Gao P et al (2011) Treatment of major laparoscopic bile duct injury: a long-term follow-up result. Am Surg 77:1584–1588

    Article  Google Scholar 

  20. Stewart L, Way LW (2009) Laparoscopic bile duct injuries: timing of surgical repair does not influence success rate. A multivariate analysis of factors influencing surgical outcomes HPB 11:516–522. https://doi.org/10.1111/j.1477-2574.2009.00096.x

    Article  PubMed  Google Scholar 

  21. Perera MTPR, Silva MA, Hegab B et al (2011) Specialist early and immediate repair of post-laparoscopic cholecystectomy bile duct injuries is associated with an improved long-term outcome. Ann Surg 253:553–560. https://doi.org/10.1097/SLA.0b013e318208fad3

    Article  PubMed  Google Scholar 

  22. de Reuver PR, Grossmann I, Busch OR et al (2007) Referral pattern and timing of repair are risk factors for complications after reconstructive surgery for bile duct injury. Ann Surg 245:763–770. https://doi.org/10.1097/01.sla.0000252442.91839.44

    Article  PubMed  PubMed Central  Google Scholar 

  23. Ford JA, Soop M, Du J et al (2012) Systematic review of intraoperative cholangiography in cholecystectomy. Br J Surg 99:160–167. https://doi.org/10.1002/bjs.7809

    Article  CAS  PubMed  Google Scholar 

  24. Sajid M, Leaver C, Haider Z et al (2012) Routine on-table cholangiography during cholecystectomy: a systematic review. Ann R Coll Surg Engl 94:375–380. https://doi.org/10.1308/003588412X13373405385331

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Slim K, Martin G (2013) Does routine intra-operative cholangiography reduce the risk of biliary injury during laparoscopic cholecystectomy? An evidence-based approach. J Visc Surg 150:321–324. https://doi.org/10.1016/j.jviscsurg.2013.06.002

    Article  CAS  PubMed  Google Scholar 

  26. Sanjay P, Tagolao S, Dirkzwager I, Bartlett A (2012) A survey of the accuracy of interpretation of intraoperative cholangiograms. HPB 14:673–676. https://doi.org/10.1111/j.1477-2574.2012.00501.x

    Article  PubMed  PubMed Central  Google Scholar 

  27. Hublet A, Dili A, Lemaire J et al (2009) Laparoscopic ultrasonography as a good alternative to intraoperative cholangiography (IOC) during laparoscopic cholecystectomy: results of prospective study. Acta Chir Belg 109:312–316

    Article  CAS  Google Scholar 

  28. Dili A, Bertrand C (2017) Laparoscopic ultrasonography as an alternative to intraoperative cholangiography during laparoscopic cholecystectomy. World J Gastroenterol 23:5438–5450. https://doi.org/10.3748/wjg.v23.i29.5438

    Article  PubMed  PubMed Central  Google Scholar 

  29. Pietrafitta JJ, Schultz LS, Graber JN et al (1991) Cholecystcholangiography during laparoscopic cholecystectomy: cholecystcholangiography or cystic duct cholangiography. J Laparoendosc Surg 1:197–206

    Article  CAS  Google Scholar 

  30. Pesce A, Piccolo G, La Greca G, Puleo S (2015) Utility of fluorescent cholangiography during laparoscopic cholecystectomy: a systematic review. World J Gastroenterol 21:7877–7883. https://doi.org/10.3748/wjg.v21.i25.7877

    Article  PubMed  PubMed Central  Google Scholar 

  31. Dip FD, Asbun D, Rosales-Velderrain A et al (2014) Cost analysis and effectiveness comparing the routine use of intraoperative fluorescent cholangiography with fluoroscopic cholangiogram in patients undergoing laparoscopic cholecystectomy. Surg Endosc 28:1838–1843. https://doi.org/10.1007/s00464-013-3394-5

    Article  PubMed  Google Scholar 

  32. Ahmad G, Gent D, Henderson D et al (2015) Laparoscopic entry techniques. Cochrane Database Syst Rev 8:CD006583. https://doi.org/10.1002/14651858.CD006583.pub4

    Article  PubMed  Google Scholar 

  33. Alves A, Farges O, Nicolet J et al (2003) Incidence and consequence of an hepatic artery injury in patients with postcholecystectomy bile duct strictures. Ann Surg 238:93–96. https://doi.org/10.1097/01.sla.0000074983.39297.c5

    Article  PubMed  PubMed Central  Google Scholar 

  34. Ball CG, MacLean AR, Kirkpatrick AW et al (2006) Hepatic vein injury during laparoscopic cholecystectomy: the unappreciated proximity of the middle hepatic vein to the gallbladder bed. J Gastrointest Surg Off J Soc Surg Aliment Tract 10:1151–1155. https://doi.org/10.1016/j.gassur.2006.04.012

    Article  Google Scholar 

  35. Sartelli M, Catena F, Biancafarina A et al (2014) Use of FLOSEAL hemostatic matrix for control of hemostasis during laparoscopic cholecystectomy for acute cholecystitis: a multicenter historical control group comparison (the GLA study gelatin matrix for acute cholecystitis). J Laparoendosc Adv Surg Tech A 24:837–841. https://doi.org/10.1089/lap.2013.0495

    Article  PubMed  Google Scholar 

  36. Alrajraji M, Nawawi A, Jamjoom R, Qari Y, Aljiffry M (2016) Delayed hemobilia due to hepatic artery pseudo-aneurysm: a pitfall of laparoscopic cholecystectomy. BMC Surg:16–17. https://doi.org/10.1186/s12893-016-0175-9

  37. Jabbari Nooghabi A, Hassanpour M, Jangjoo A (2016) Consequences of lost gallstones during laparoscopic cholecystectomy: a review article. Surg Laparosc Endosc Percutan Tech 26:183–192. https://doi.org/10.1097/SLE.0000000000000274

    Article  PubMed  Google Scholar 

  38. Hawasli A, Schroder D, Rizzo J et al (2002) Remote complications of spilled gallstones during laparoscopic cholecystectomy: causes, prevention, and management. J Laparoendosc Adv Surg Tech A 12:123–128. https://doi.org/10.1089/10926420252939664

    Article  PubMed  Google Scholar 

  39. Woodfield JC, Rodgers M, Windsor JA (2004) Peritoneal gallstones following laparoscopic cholecystectomy: incidence, complications, and management. Surg Endosc 18:1200–1207. https://doi.org/10.1007/s00464-003-8260-4

    Article  CAS  PubMed  Google Scholar 

  40. Capolupo GT, Mascianà G, Carannante F, Caricato M (2018) Spilled gallstones simulating peritoneal carcinomatosis: a case report and literature review. Int J Surg Case Rep 48:113–121. https://doi.org/10.1016/j.ijscr.2018.04.016

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Ahmad J, Mayne A, Zen Y et al (2014) Spilled gallstones during laparoscopic cholecystectomy. Ann R Coll Surg Engl 96:e18–e20. https://doi.org/10.1308/003588414X13946184900444

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  42. Janssen IMC, Swank DJ, Boonstra O et al (2003) Randomized clinical trial of ultrasonic versus electrocautery dissection of the gallbladder in laparoscopic cholecystectomy. Br J Surg 90:799–803. https://doi.org/10.1002/bjs.4128

    Article  CAS  PubMed  Google Scholar 

  43. Lee CM, Stewart L, Way LW (2000) Postcholecystectomy abdominal bile collections. Arch Surg 135:538–544. https://doi.org/10.1001/archsurg.135.5.538

    Article  CAS  PubMed  Google Scholar 

  44. Felekouras E, Petrou A, Neofytou K et al (2015) Early or delayed intervention for bile duct injuries following laparoscopic cholecystectomy? A dilemma looking for an answer. Gastroenterol Res Pract 2015:104235. https://doi.org/10.1155/2015/104235

    Article  PubMed  PubMed Central  Google Scholar 

  45. Kapoor VK (2007) Bile duct injury repair: when? what? who? J Hepato-Biliary-Pancreat Surg 14:476–479. https://doi.org/10.1007/s00534-007-1220-y

    Article  Google Scholar 

  46. Copelan A, Bahoura L, Tardy F et al (2015) Etiology, diagnosis, and management of bilomas: a current update. Tech Vasc Interv Radiol 18:236–243. https://doi.org/10.1053/j.tvir.2015.07.007

    Article  PubMed  Google Scholar 

  47. Tzovaras G, Dervenis C (2006) Vascular injuries in laparoscopic cholecystectomy: an underestimated problem. Dig Surg 23:370–374. https://doi.org/10.1159/000097951

    Article  PubMed  Google Scholar 

  48. Wise Unger S, Glick GL, Landeros M, Cystic Duct Leak Study Group (1996) Cystic duct leak after laparoscopic cholecystectomy. Surg Endosc 10:1189–1193. https://doi.org/10.1007/s004649900276

    Article  CAS  PubMed  Google Scholar 

  49. Mishra PK, Saluja SS, Nayeem M, Sharma BC, Patil N (2015) Bile duct injury—from injury to repair: an analysis of management and outcome. Indian J Surg 77:536–542. https://doi.org/10.1007/s12262-013-0915-3

    Article  PubMed  Google Scholar 

  50. Bansal VK, Krishna A, Misra MC, Prakash P, Kumar S, Rajan K, Babu D, Garg P, Kumar A, S R (2015) Factors affecting short-term and long-term outcomes after bilioenteric reconstruction for post-cholecystectomy bile duct injury: experience at a tertiary care centre. Indian J Surg 77:472–479. https://doi.org/10.1007/s12262-013-0880-x

    Article  PubMed  Google Scholar 

  51. Kapoor VK. Safe cholecystectomy A-to-Z. Lucknow: Shubham Book Distrubutors; 2010

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Correspondence to Virinder Kumar Bansal.

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This consensus statement is for general guidance only; the recommendations made in this statement do not cover all situations and scenarios and may be modified depending upon the infrastructure and the expertise available in a given situation.

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The term common bile duct (CBD) has been used in these guidelines. At most places, it means and includes common hepatic duct (CHD) also.

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Bansal, V.K., Misra, M., Agarwal, A.K. et al. SELSI Consensus Statement for Safe Cholecystectomy—Prevention and Management of Bile Duct Injury—Part B. Indian J Surg 83 (Suppl 3), 611–624 (2021). https://doi.org/10.1007/s12262-019-01994-1

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