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Right vs Left Colon Cancers Have Comparable Survival: a Decade’s Experience

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Abstract

The aim of this study is to compare survival rates between right and left colon cancers following curative intent oncologic resection. The data of right- (between cecum and proximal two-thirds of the transverse colon) and left-sided (between distal one-third of the transverse colon and distal sigmoid colon) colon cancer patients, operated with curative intent including central vascular ligation between January 2005 and 2015, were recorded in a prospectively compiled database. Epidemiologic and clinical characteristics (laparoscopic resection, multivisceral resection, lymph node yield, metastatic lymph node yield, pathologic stage, duration of operation), early post-operative results, and overall 5-year survival rates were abstracted. A total of 426 patients were included. There were no differences in epidemiologic and clinical characteristics between two groups (p > 0.05), except a higher median lymph node yield in right-sided colon cancers (31 vs 24, p ˂ 0.001). Cox regression analysis identified no differences in overall 5-year survival rates between right (76.9%) and left colon (76.4%) cancers (p = 0.752). In right-sided colon cancer group, 5-year overall survival was significantly higher with laparoscopic resection (60.5% vs 78.9%, p = 0.008). There were no significant differences in left-sided colon cancer group per surgical approach (p = 0.357). Curative intent oncologic resection with central vascular ligation provided similar overall 5-year survival rates in right- vs left-sided colon cancers. Laparoscopic resection provided a significantly increased 5-year overall survival in right colon cancer group.

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Authors and Affiliations

  1. Istanbul Faculty of Medicine, General Surgery Department, Istanbul University, Istanbul, Turkey

    Metin Keskin, Adem Bayraktar, Cemil Burak Kulle & Mehmet Türker Bulut

  2. School of Medicine, General Surgery Department, Yeni Yüzyıl University, Istanbul, Turkey

    Emre Sivrikoz

  3. Istanbul Faculty of Medicine, Pathology Department, Istanbul University, Istanbul, Turkey

    Gülçin Yeğen

  4. School of Medicine, General Surgery Department, Koç University, Istanbul, Turkey

    Dursun Buğra & Emre Balık

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  1. Metin Keskin
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  2. Emre Sivrikoz
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  4. Adem Bayraktar
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Correspondence to Cemil Burak Kulle.

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Keskin, M., Sivrikoz, E., Yeğen, G. et al. Right vs Left Colon Cancers Have Comparable Survival: a Decade’s Experience. Indian J Surg 82, 134–141 (2020). https://doi.org/10.1007/s12262-019-01900-9

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  • DOI: https://doi.org/10.1007/s12262-019-01900-9

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