Abstract
Malignant phyllodes tumors are rare fibroepithelial tumor accounting for 0.3 to 0.9% of all breast neoplasms. Distant metastasis occurs in 10–20% of patients, most common sites being the lung and bones. Skeletal muscle metastasis is rarely seen in malignant phyllodes. So far, only one case of malignant phyllodes tumor metastatic to skeletal muscle has been reported in the literature. A 45-year-old perimenopausal woman presented with a lump in her left breast and swelling over the right calf region. Workup showed mass in left breast and metastasis to the right calf muscle along with the lung and multiple bone metastases. She was started on ifosfamide- and adriamycin-based chemotherapy along with zolendronic acid. She received palliative radiotherapy to the spine and right calf region for pain. After 3 cycles, there was progression, so patient was started on second-line chemotherapy with gemcitabine and docetaxel. Patient developed severe pancytopenia after 3 cycles, so further chemotherapy was stopped as patient was not tolerating it.
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Kim DJ, Yoon CS, Koo JS, Chung WH, Haam S, Lee DY et al (2009) Metastasis to the skeletal muscle from a malignant phyllodes tumor of the breast: a case report. J Korean Soc Magn Reson Med 13:101–105
Khosravi-Shahi P (2011) Managemaent of non-metastatic phyllodes tumors of the breast: review of the literature. Surg Oncol 20:143–148
Ben Hassouna J, Damak T, Gamoudi A, Chargui R, Khomsi F, Mahjoub S et al (2006) Phyllodes tumors of the breast: a case series of 106 patients. Am J Surg 192:141–147
Santiago Chinchilla A, Ramos Font C, Custodio Rebello Aguirre A, Navarro-Pelayo Lainez M, Palacios Gerona H et al (2010) Malignant phyllodes tumor of the breast with lymph node metastases shown by FDG PET-CT. Rev Esp Med Nucl 29:314–315
Suarez Roa Mde L, Ruiz Godoy Riveria LM, Vela Chavez T, Perez Sanchez M, Meneses Garcia A (2007) Breast malignant phyllodes tumor metastasizing to soft tissues of oral cavity. Clin Transl Oncol 9:258–261
Salamoun WI (1993) Malignant cystosarcoma phyllodes: an unusual presentation and review of the literature. J Med Liban 41:40–43
Barth RJ Jr, Wells WA, Mitchell SE, Cole BF (2009) A prospective, multi-institutional study of adjuvant radiotherapy after resection of malignant phyllodes tumors. Ann Surg Oncol 16:2288–2294
Belkacemi Y, Bousquet G, Marsiglia H, Ray-Coquard I, Magne N, Malard Y et al (2008) Phyllodes tumor of the breast. Int J Radiat Oncol Biol Phys 70:492–500
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Mate, P.U., Madholia, V. & Choudhary, A. A Rare Case of Malignant Phyllodes Tumor of Breast Metastatic to the Skeletal Muscle. Indian J Surg 80, 385–387 (2018). https://doi.org/10.1007/s12262-017-1693-0
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DOI: https://doi.org/10.1007/s12262-017-1693-0