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Effects of an Educational Module in Rationalizing Surgical Prophylaxis

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Abstract

Assessment of current antibiotic prescribing patterns is an important step towards appropriate use of antimicrobial agents. This study was planned to know the surgical prophylaxis practices and the influence of educational intervention. In this educational interventional study, only clean and clean-contaminated surgeries were included. Preinterventional study was done by collecting data regarding the use of surgical prophylaxis in the Department of Surgery. After analyzing the preinterventional data, educational intervention was done. A pretest questionnaire was given to all the surgeons to assess knowledge and practice of surgical prophylaxis in our institute. The questionnaire was designed to collect information regarding the use of prophylactic antibiotic, its duration, time of administration, and prevention of surgical site infections (SSI). In our study, third-generation cephalosporin was used in maximum cases in preinterventional analysis and prophylaxis was continued for 3–5 days. Surgeon’s decision in selecting a prophylactic agent was based on information taken from departmental colleagues or drug companies. Two or more doses of antibiotic were used even when duration of surgery did not exceed more than two and half hours. Definite improvement was seen after the education where single antibiotic was used as prophylactic drug and the first dose of antibiotic was administered 30 to 60 min before incision. This shows that educational intervention makes a change in antibiotic prescribing habit. Hence, there is an urgent need for adoption of specific guidelines to ensure standardization of surgical antibiotic prophylaxis practices in hospitals.

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References

  1. Burke JP (2003) Infection control—a problem for patient safety. N Engl J Med 348:651–656

    Article  PubMed  Google Scholar 

  2. Gagliardi AR, Fenech D, Eskicioglu C, Nathens AB, McLeod R (2009) Factors influencing antibiotic prophylaxis for surgical site infection prevention in general surgery: a review of the literature. Can J Surg 52(6):481–489

    PubMed  PubMed Central  Google Scholar 

  3. Mangram AJ (1999) Hospital Infection Control Practices Advisory Committee (HICPAC) and Centers for Disease Control and Prevention (CDC). Guidelines for prevention of surgical site infection. Infect Control Hosp Epidemiol 24(4):247–278

    Google Scholar 

  4. Kanji S, Devlin JW (2005) Antimicrobial prophylaxis in surgery. In: Dipiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM (eds) Pharmacotherapy—a pathophysiologic approach, 6th edn. Mc Graw Hill, New York, pp 2217–2229

    Google Scholar 

  5. Kernodle DS, Kaiser AB (1995) Surgical and trauma-related infections. In: Mandell GL, Bennet JE, Dolin R (eds) Principles and practice of infectious diseases, 4th edn. Churchill Livingstone, New York, pp 2742–2755

    Google Scholar 

  6. Meakins J (1994) Prophylactic antibiotics. In: Meakins J (ed) Surgical infections. Diagnosis and treatment. Scientific American Inc, New York, pp 139–149

    Google Scholar 

  7. Hecker MT, Aron DC, Patel NP et al (2003) Unnecessary use of antimicrobials in hospitalized patients: current patterns of misuse with an emphasis on the antianaerobic spectrum of activity. Arch Intern Med 163:972–978

    Article  PubMed  Google Scholar 

  8. Privitera G, Scarpellini P, Ortisi G et al (1991) Prospective study of Clostridium difficile intestinal colonization and disease following single dose antibiotic prophylaxis in surgery. Antimicrob Agents Chemother 35:208–210

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  9. Dettenkofer M, Forster DH, Ebner W, Gastmeier P, Ruden H, Daschner FD (2002) The practice of perioperative antibiotic prophylaxis in eight German hospitals. Infection 30:164–167

    Article  PubMed  CAS  Google Scholar 

  10. Kulkarni RA, Kochhar PH, Dargude VA, Rajadhyakshya SS, Thatte UM (2005) Patterns of antimicrobial use by surgeons in India. Indian J Surg 67:308–315

    Google Scholar 

  11. Rehan HS, Kakkar AK, Goel S (2010) Surgical antibiotic prophylaxis in a tertiary care teaching hospital in India. Int J Infect Control 6(2):1–6

    Google Scholar 

  12. ASHP (1999) ASHP therapeutic guidelines on antimicrobial prophylaxis in surgery. American Society of Health-System Pharmacist. Am J Health Pharm 56:1839–1888

    Google Scholar 

  13. Bull AL, Russo PL, Friedman ND, Bennett NJ, Boardman CJ, Richards MJ (2006) Compliance with surgical antibiotic prophylaxis—reporting from a statewide surveillance programme in Victoria, Australia. J Hosp Infect 63:140–147

    Article  PubMed  CAS  Google Scholar 

  14. Bedouch P, Labarere J, Chirpaz E, Allenet B, Lepape A, Fourny M, Pavese P, Girardet P, Merloz P, Saragagliaa D, Calop J, Francois P (2004) Compliance with guidelines on antibiotic prophylaxis in total hip replacement surgery: results of a retrospective study of 416 patients in a teaching hospital. Infect Control Hosp Epidemiol 25:302–307

    Article  PubMed  Google Scholar 

  15. Al-Azzam SI, Alzoubi KH, Mhaidat NM, Haddadin RD, Masadeh MM, Tumah HN, Magableh A, Maraqa NK (2012) Preoperative antibiotic prophylaxis practice and guideline adherence in Jordan: a multi centre study in Jordanian hospitals. J Infect Dev Ctries 6(10):715–720

    Article  PubMed  Google Scholar 

  16. Hosoglu S, Sunbul M, Erol S, Altindis M, Caylan R, Demirdag K, Uemak H, Mendes H, Geyik MF, Turgut H, Gundes S, Doyuk EK, Aldemir M, Dokucu A (2003) A national survey of surgical antibiotic prophylaxis in Turkey. Infect Control Hosp Epidemiol 24:758–761

    Article  PubMed  Google Scholar 

  17. Pons-Busom M, Aguas-compaired M, Delas J, Eguileor-Partearroyo B (2004) Compliance with local guidelines for antibiotic prophylaxis in surgery. Infect Control Hosp Epidemiol 25:308–312

    Article  PubMed  Google Scholar 

  18. Chakane M, Purandare S (2012) A single dose antibiotic prophylaxis in clean surgery: our experience. Indian J Appl Res 2:2122–2123

    Google Scholar 

  19. Chandrashekhar C, Seenu V, Misra MC, Rattan A, Kapur BM, Singh R (1996) Risk factor for wound infections following cholecystectomy. Trop Gastroenterol 17(4):230–232

    PubMed  CAS  Google Scholar 

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Conflict of Interest

The authors declare that they have no competing interests.

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Correspondence to Neena Nagdeo.

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This project is a part of ICMR ASPIC Programme: Antimicrobial Stewardship, Prevention and Infection Control conducted by CMC Vellore, India. Our Institute is one of the participating centers in this study.

Appendices

Annexure –I Proforma

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Annexure –II Pre &Post Test Questionnaire

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Nagdeo, N., Sonarkar, R., Thombare, V.R. et al. Effects of an Educational Module in Rationalizing Surgical Prophylaxis. Indian J Surg 77, 290–296 (2015). https://doi.org/10.1007/s12262-015-1297-5

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  • DOI: https://doi.org/10.1007/s12262-015-1297-5

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