Skip to main content

Advertisement

SpringerLink
Log in

Polymorphous Low-Grade Adenocarcinoma (PLGA) in an 18-Year-Old Male

  • Case Report
  • Published:
Indian Journal of Surgery Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

Polymorphous low-grade adenocarcinoma (PLGA) is a minor salivary gland tumor with a low malignant potential. It is twice more common in females, with a mean age of presentation at 59 years. It is a very slow-growing tumor with mean duration of symptoms that range from 27 months to as long as 40 years. We report a case of a male patient who was found to have PLGA with symptoms since birth. The patient was treated with wide local excision with good results. The lip is a rare location for PLGA, and its occurrence in adolescent age groups is even rarer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Beltran D, Faquin WC, Gallagher G, August M (2006) Selective immunohistochemical comparison of polymorphous low-grade adenocarcinoma and adenoid cystic carcinoma. J Oral Maxillofac Surg 64(3):415–423

    Article  PubMed  Google Scholar 

  2. Buchner A, Merrell PW, Carpenter WM (2007) Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med 36(4):207–214

    Article  PubMed  Google Scholar 

  3. Castle JT, Thompson LD, Frommelt RA, Wenig BM, Kessler HP (1999) Polymorphous low grade adenocarcinoma: a clinicopathologic study of 164 cases. Cancer 86(2):207–219

    Article  PubMed  CAS  Google Scholar 

  4. Pintor MF, Figueroa L, Martinez B (2007) Polymorphous low grade adenocarcinoma: review and case report. Med Oral Patol Oral Cir Bucal 12(8):E549–E551

    PubMed  Google Scholar 

  5. Kumar M, Stivaros N, Barrett AW, Thomas GJ, Bounds G, Newman L (2004) Polymorphous low-grade adenocarcinoma—a rare and aggressive entity in adolescence. Br J Oral Maxillofac Surg 42(3):195–199

    Article  PubMed  CAS  Google Scholar 

  6. Pogodzinski MS, Sabri AN, Lewis JE, Olsen KD (2006) Retrospective study and review of polymorphous low-grade adenocarcinoma. Laryngoscope 116(12):2145–2149

    Article  PubMed  Google Scholar 

  7. Epivatianos A, Iordanides S, Zaraboukas T, Antoniades D (2005) Adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of minor salivary glands: a comparative immunohistochemical study using the epithelial membrane and carcinoembryonic antibodies. Oral Dis 11(3):175–180

    Article  PubMed  CAS  Google Scholar 

  8. Vargas PA, Cheng Y, Barrett AW, Craig GT, Speight PM (2008) Expression of Mcm-2, Ki-67 and geminin in benign and malignant salivary gland tumours. J Oral Pathol Med 37(5):309–318

    Article  PubMed  CAS  Google Scholar 

  9. Dequanter D, Andry G, Lothaire P, Larsimont D, Deraemaecker R (2005) Wide localized excision and reconstruction for minor salivary gland tumours. B-ENT 1(4):187–190

    PubMed  CAS  Google Scholar 

  10. Paleri V, Robinson M, Bradley P (2008) Polymorphous low-grade adenocarcinoma of the head and neck. Curr Opin Otolaryngol Head Neck Surg 16(2):163–169

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

None is declared.

Consent

The patient's consent was obtained for publication of this case report.

Author information

Authors and Affiliations

  1. Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India

    Umakant Gaud & Manoj Pandey

  2. Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India

    Mridula Shukla & Mohan Kumar

Authors
  1. Mridula Shukla
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Umakant Gaud
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mohan Kumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Manoj Pandey
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mridula Shukla.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shukla, M., Gaud, U., Kumar, M. et al. Polymorphous Low-Grade Adenocarcinoma (PLGA) in an 18-Year-Old Male. Indian J Surg 75, 153–155 (2013). https://doi.org/10.1007/s12262-012-0804-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12262-012-0804-1

Keywords

Search

Navigation