Abstract
Propofol, an intravenously administered, centrally acting sedative/hypnotic, is a popular medication for anesthesia and sedation due to rapid onset, controllability and short recovery time. Prolonged propofol infusions, (>48 h) with elevated doses (>67 mcg/kg/min) may result in a rare but fatal condition known as the Propofol Related Infusion Syndrome (PRIS). This is a case of severe metabolic acidosis and refractory hyperkalemia in a 53 year old female with polytrauma on a continuous propofol infusion that was associated with fatal outcome.
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Agrawal, N., Rao, S. & Nair, R. A Death Associated with Possible Propofol Infusion Syndrome. Indian J Surg 75 (Suppl 1), 407–408 (2013). https://doi.org/10.1007/s12262-012-0754-7
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DOI: https://doi.org/10.1007/s12262-012-0754-7