Indian Journal of Surgery

, Volume 76, Issue 3, pp 193–198 | Cite as

A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

  • Sonia Gulati
  • Ashia Qureshi
  • Anurag SrivastavaEmail author
  • Kamal Kataria
  • Pratik Kumar
  • Acharya Balakrishna Ji
Original Article


To compare the healing of chronic wounds with honey dressing vs. Povidone iodine dressing in adult subjects with chronic wounds of ≥6 weeks of duration, attending wound care clinic in Surgical Out Patient Department of All India Institute of Medical Sciences, Surgical Out Patient Department of Jai Prakash Narayan Apex Trauma center, New Delhi. Forty five subjects were randomized into two groups i.e., Honey & Povidone iodine dressing group. Dressing was done on alternate day basis for 6 weeks of followup period. Main outcome measure was complete healing at 6 weeks. Wound healing status was assessed at 2 weekly intervals till 6 weeks. Seven out of 22 subjects in honey treated group achieved complete healing as compared to none out of 20 subjects in Povidone iodine treated group. There was a significant decrease in the wound surface area, pain score & increase in comfort score in Honey dressing group in comparison to the Povidone Iodine group at 0.05 level of significance. Honey dressing is highly effective in achieving healing in chronic wounds as compared to Povidone iodine dressing.


Honey dressing Povidone iodine dressing Chronic wound healing Occlusive dressing Randomized trial 


  1. 1.
    Zumla A, Lulat A (1989) Honey—a remedy rediscovered. J Roy Soc Med 82:384–385PubMedCentralPubMedGoogle Scholar
  2. 2.
    Armon PJ (1980) The use of honey in the treatment of infected wounds. Trop Doct 10:91PubMedGoogle Scholar
  3. 3.
    Molan PC (2006) The evidence supporting the use of honey as a wound dressing. Int J Low Extrem 5:40CrossRefGoogle Scholar
  4. 4.
    Effem SE (1988) Clinical observations on the wound healing properties of honey. Br J Surg 75:679–681CrossRefGoogle Scholar
  5. 5.
    Molan PC, Betts JA (2004) Clinical usage of honey as a wound dressing: an update. J Wound Care 13(9):353–356PubMedCrossRefGoogle Scholar
  6. 6.
    White JW (1975) Composition of honey. In: Crane E (ed) Honey: a comprehensive survey. Heinemann, London, pp 157–206Google Scholar
  7. 7.
    Luciana P, Fernandez SL (2005) Venous ulcer: epidemiology, physiopathology, diagnosis and treatment. Int Soc Dermatol 44:449–456CrossRefGoogle Scholar
  8. 8.
    Yapucu Güneş U, Eşer I (2007) Effectiveness of a honey dressing for healing pressure ulcers. J Wound Ostomy Cont Nurs 34(2):184–190CrossRefGoogle Scholar
  9. 9.
    Okeniyi JA, Olubanjo OO, Ogunlesi TA, Oyelami OA (2005) Comparison of healing of incised abscess wounds with honey and EUSOL dressing. J Alternative Compl Med 11(3):511–513CrossRefGoogle Scholar
  10. 10.
    Subrahmanyam M (1998) A prospective randomized clinical and histological study of superficial burn wound healing with honey and silver sulfadiazine. Burns 24(2):157–161PubMedCrossRefGoogle Scholar
  11. 11.
    Wood B, Rademaker M, Molan PC (1997) Manuka honey, a low cost leg ulcer dressing. N Z Med J 110(1040):107PubMedGoogle Scholar
  12. 12.
    Subrahmanyam M (1994) Honey-impregnated gauze versus amniotic membrane in the treatment of burns. Burns 20(4):331–333PubMedCrossRefGoogle Scholar
  13. 13.
    Ndayisaba G, Bazira L, Habonimana E, Muteganya D (1993) Clinical and bacteriological results in wounds treated with honey. J Orthop Surg 7(2):202–204Google Scholar
  14. 14.
    Weheida SM, Nagubi HH, El-Banna HM, Marzouk S (1991) Comparing the effects of two dressing techniques on healing of low grade pressure ulcers. J Med Res Inst 12(2):259–278Google Scholar
  15. 15.
    Kramer SA (1999) Effect of povidone-iodine on wound healing: a review. J Vasc Nurs 17(1):17–23PubMedCrossRefGoogle Scholar
  16. 16.
    Efem SEE (1988) Clinical observations on the wound healing properties of honey. Br J Surg 75:679–681PubMedCrossRefGoogle Scholar
  17. 17.
    Hamdy MH, El Banby MA, Khakifa KI, Gad EM (1988) The antimicrobial effect of honey in the management of septic wounds. Proceedings of the Fourth International Conference on Apiculture in Tropical Climates, Cairo, Egypt 6–10 November London, UK; International Bee Research AssociationGoogle Scholar
  18. 18.
    Mphande AN, Killowe C, Phalira S, Jones HW, Harrison WJ (2007) Effects of honey and sugar dressings on wound healing. J Wound Care 16(7):317–319PubMedCrossRefGoogle Scholar
  19. 19.
    Subrahmanyam M (1991) Topical application of honey in treatment of burns. Br J Surg 78(4):497–498PubMedCrossRefGoogle Scholar
  20. 20.
    Medhi B, Puri A, Upadhyay S, Kaman L (2008) Topical application of honey in the treatment of wound healing: a metaanalysis. Alternative Med 10(4):166–169Google Scholar
  21. 21.
    Atiyeh BS, Al-Amm CA, El-Musa KA, Sawwaf A, Dham R (2003) The effect of moist and moist exposed dressings on healing and barrier function restoration of partial thickness wounds. Eur J Plast Surg 26:5–11Google Scholar
  22. 22.
    Singh A, Halder S, Menon G, Chumber S, Misra MC, Sharma LK, Srivastava A (2004) Meta-analysis of randomized controlled trials on hydrocolloid occlusive dressing versus conventional gauze dressing in the healing of chronic wounds. Asian J Surg 27(4):326–332PubMedCrossRefGoogle Scholar
  23. 23.
    Kwong YL, Chung CH (1985) The use of Tegaderm transparent dressing in the outpatient management of partial thickness burns. J Hong Kong Med Assoc 37(4):28–32Google Scholar

Copyright information

© Association of Surgeons of India 2012

Authors and Affiliations

  • Sonia Gulati
    • 1
  • Ashia Qureshi
    • 1
  • Anurag Srivastava
    • 2
    Email author
  • Kamal Kataria
    • 2
  • Pratik Kumar
    • 3
  • Acharya Balakrishna Ji
    • 4
  1. 1.College of nursingAIIMSNew DelhiIndia
  2. 2.Department of SurgeryAIIMSNew DelhiIndia
  3. 3.Department of Medical PhysicsAIIMSNew DelhiIndia
  4. 4.Patanjali YogpithHaridwarIndia

Personalised recommendations