Abstract
Schwannoma arising in a lymph node is an extremely rare primary mesenchymal tumor of the lymph node. Although intranodal schwannoma is benign, this lesion in a lymph node may be initially alarming and it may suggest a diagnosis of intranodal metastasis from a spindle cell tumor. Microscopic examination of tumor shows Antoni A areas, which are moderate to highly cellular areas of elongated cells arranged in fascicles, and Antoni B areas, which are hypocellular areas with myxoid and microcystic change. Tumor cell morphology is similar in both areas with elongated shape and regular oval nuclei. Immunohistochemistry report shows strong and diffuse positivity for S-100 which is consistent with Schwann cell origin. We report a rare case of intranodal schwannoma arising in the hilar lymph node with its clinical, light microscopic, and immunohistochemical findings
This is a preview of subscription content, log in via an institution to check access.
References
Griffiths AP, Ironside JW, Gray C (1991) True neurilemmoma arising in a lymph node in infancy. Histopathology 18(2):180–183
Piana S, Gelli MC, Cavazza A, Serra L, Gardini G (2002) Ancient schwannoma arising in a lymph node: report of a case and review of literature. Pathol Res Pract 198(1):51–54
Reinus C, Shutin O, Reissman P (2004) Intranodal schwannoma presenting as an adrenal mass. Histopathology 45(1):95–96
Fletcher CD (2000) Primary neuroectodermal tumours. In: Diagnostic histopathology of tumours. Churchill Livingstone, p 1686
Weiss SW, Gnepp DR, Bratthauer GL (1989) Palisaded myofibroblastoma. A benign mesenchymal tumour of lymph node. Am J Surg Pathol 13:341–346
Jung JH, Jinyoung Y, Seok JK, Kyo YL (2009) Schwannoma arising in a lymph node. Korean J Pathol 43:217–213
Suster S, Rosai J (1989) Intranodal haemorrhagic spindle-cell tumor with “amianthoid” fibres. Report of six cases of a distinctive mesenchymal neoplasm of the inguinal region that simulates Kaposi’s sarcoma. Am J Surg Pathol 13:347–357
Nasrin S, Shahriar ZS (2008) Schwannoma in a perigastric lymph node: a rare case report. Iran J Pathol 3(1):43–46
Hollowood K, Pease C, Mackay AM, Fletcher CD (1991) Sarcomatoid tumors of lymph nodes showing follicular dendritic cell differentiation. J Pathol 163(3):205–206
Chan JKC (1997) Vascular tumors with a prominent spindle cell component. Curr Diagnost Pathol 4(2):76–90
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nath, P., Sharma, H. & Chatterjee, T. A Rare Case of Hilar Lymph Node Schwannoma. Indian J Surg 75 (Suppl 1), 233–235 (2013). https://doi.org/10.1007/s12262-012-0652-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12262-012-0652-z