Indian Journal of Surgery

, Volume 75, Supplement 1, pp 9–11 | Cite as

Castleman’s Disease—A Rare Diagnosis in the Retroperitoneum

  • Dakshyani S. Nirhale
  • Ramchandra N. Bharadwaj
  • Virendra S. Athavale
  • Ruchita K. GuptaEmail author
  • Charit Bora
Case Report


Abdominal masses have always been a dilemma for the surgeons and this problem is more so in retroperitoneal masses. In our case, the patient presented with retroperitoneal mass in the left lumbar region with no other specific local or systemic symptoms. The diagnosis of Castleman’s disease was established only after histopathological examination of the mass after resection. Castleman’s disease is an angiofollicular lymph node hyperplasia presenting either as a localized or a systemic disease. In our case, the patient presented with the localized form of the disease and as it is a rare presentation we are presenting this case.


Castleman’s disease Retroperitoneal mass Lymph node hyperplasia 


  1. 1.
    Symmers D (1921) Primary hemangiolymphoma of the hemal nodes: an unusual variety of malignant tumour. Arch Intern Med 28:467–474CrossRefGoogle Scholar
  2. 2.
    Castleman B, Iverson L, Menendez VP (1956) Localized mediastinal lymph-node hyperplasia resembling thymoma. Cancer 9:822–830PubMedCrossRefGoogle Scholar
  3. 3.
    Keller AR, Hochholzer L, Castleman B (1972) Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 29:670–683PubMedCrossRefGoogle Scholar
  4. 4.
    Herrada J, Cabanillas F, Rice L, Manning J, Pugh W (1998) The clinical behavior of localized and multicentric Castleman disease. Ann Intern Med 128:657–666PubMedCrossRefGoogle Scholar
  5. 5.
    Larroche C, Cacoub P, Godeau P (1996) La maladie de Castleman. Rev Méd Interne 17:1003–1013PubMedCrossRefGoogle Scholar
  6. 6.
    Bucher P, Chassot G, Zufferey G, Ris F, Huber O, Morel P (2005) Surgical management of abdominal and retroperitoneal Castleman’s disease. World J Surg Oncol 3:33–38PubMedCentralPubMedCrossRefGoogle Scholar
  7. 7.
    Fields S, Bar-ziv J, Portnoy O, Sasson T, Sherman Y, Libson E (1995) Radiologic spectrum of localised Castleman’s disease. Isr J Med Sci 31:660–669PubMedGoogle Scholar
  8. 8.
    Testa P, Pigne A, Voinnesson A, Vieillefond A, Paillas J (1980) Les hyperplasies lymphoïdes angiofolliculaires (maladie de Castleman) Premiere localisation meso-sigmoïdienne. Chirurgie 106:156–160Google Scholar

Copyright information

© Association of Surgeons of India 2011

Authors and Affiliations

  • Dakshyani S. Nirhale
    • 1
  • Ramchandra N. Bharadwaj
    • 1
  • Virendra S. Athavale
    • 1
  • Ruchita K. Gupta
    • 1
    Email author
  • Charit Bora
    • 1
  1. 1.Department of General SurgeryPadmashree Dr. D. Y. Patil Medical Hospital and Research CentrePimpriIndia

Personalised recommendations