Abstract
Ghee and honey has been advocated and used as dressing for infected wounds by Sushruta (600BC) and since 1991 in four Mumbai Hospitals. The gratifying results observed with the dressing have prompted this study which aims to establish its efficacy in five recalcitrant subset of chronic infected wounds over a three year period 2006–2009. A standardized ghee and honey dressing was used to treat: a) Eight cases of fungating malignant lesions. b) Thirteen chronic venous ulcers. c) Twenty nine diabetic foot ulcers. d) Eleven of infected ventral hernia mesh hernioplasty. e) Eleven patient with post-cesarean wound dehiscence. The dressing markedly reduced the foul odour and discharge, significantly improving the quality of life in malignant lesions. The results were equivocal in cases of venous ulcers. The results were uniformly good in the last three groups. In view of our results, as also result of innumerable Randomized Control Trials (RCTs) reported on honey dressing for infected wounds, there is substantial evidence that ghee and honey dressing has at least comparable results to other modes of treatment. The easy availability and low cost of this treatment makes it significant in developing countries. Further trials seem warranted.
Similar content being viewed by others
References
Udwadia TE (2008) Ghee and honey dressing. Rural Surg 4:1–3
Grover SK, Prasad GC (1985) Uses of Madhu in Ayurveda. J NIMA 10:7–10
Subrahmanyam M (2007) Topical application of honey for burn wound treatment – an overview. Ann Burns Fire Disasters 20:137–140
White RJ, Molan P (2005) A summary of published clinical research on honey in wound management. In White RJ, Cooper A, Molan P (Eds). Honey: a modern wound management product. Nurs Stand 20:130–143.
Ahmed AK, Hoekstra MJ, Hage J et al (2003) Honey medicated dressing: transformation of an ancient remedy into modern therapy. Ann Plast Surg 50:143–148
Cooper RA, Molan PC, Harding KG (1999) Antibacterial activity of honey against strains of Staphylococcus aureus from infected wounds. J Roy Soc Med 283–285
Allen KL, Hutchinson G, Molan PC (2000) The potential for using honey to treat wounds infected with MRSA and VRE. First World Wound Healing Congress, Melbourne
Charde MS, Fulzele SV, Satturwar PM et al (2006) Wound healing and anti-inflammatory potential of madhu-ghrita. Indian J Pharm Sci 68:26–31
Wood B, Rademaker M, Molan P (1997) Manuka honey, a low cost leg ulcer dressing. N Z Med J 110(1040):107
Jull N, Walker VP et al (2008) Randomized clinical trial of honey-impregnated dressings for venous leg ulcers. Br J Surg 95:175–182
Eddy JJ, Gideonsen MD (2005) Topical honey for diabetic foot ulcers. J Fam Pract 54:533–535
Al-Waili NS, Saloom KY (1999) Effects of topical honey on post-operative wound infections due to gram positive and gram negative bacteria following caesarian sections and hysterectomies. Eur J Med Res 4:126–130
Phuapradit W, Saropala N (1992) Topical application of honey in treatment of abdominal wound disruption. Aust N Z J Obstet Gynaecol 32:381–384
Subrahmanyam M (1998) Honey as a topical antibacterial agent for treatment of infected wounds. A prospective randomized clinical and histological study of superficial burn wound healing with honey and silver sulphadiazine. Burns 24(2):157–161
Green AE (1988) Wound healing properties of honey. Br J Surg 75:1278
Stephen-Haynes J. (2005). Implications of honey dressing within primary care. In: White RJ, Cooper A, Molan P (Eds) Honey: a modern wound management product. Wounds UK, Aberdeen. Nurs Stand 20:33–53
Hyslop PA, Hinshaw DB, Scraufstatter IU et al (1995) Hydrogen peroxide as a patent Bacteriostatic antibiotic implications for host defense. Free Radic Biol Med 19:31–37
Tonks AJ, Cooper RA, Jones KP et al (2003) Honey stimulates inflammatory cytokine production from monocytes. Cytokine 21:242–247
Tonks AJ, Cooper RA, Price AJ et al (2001) Stimulation of the tnf-alpha release in monocytes by honey. Cytokine 14:240–242
Stephen-Haynes J (2005). Implications of honey dressing within primary care. In: White RJ, Cooper A, Molan P (Eds) Honey: a modern wound management product. Wounds UK, Aberdeen, Nurs Stand 20:33–53
Molan PC, Allen KL (1996) The effect of gamma-irridation on the antibacterial activity of honey. J Pharm Pharmacol 48:1206–1209
Bell SG (2007) The therapeutic use of honey. Neonatal 26:247–251
Cooper RA, Gray D (2005) The control of wound malodour with honey based wound dressing and ointments. Wounds UK. Aberdeen 26–32
Ingle R, Levin J, Polinder K (2006) Wound healing with honey- a randomized controlled trial. S Afr Med J 96:831–835
Soffer A (1976) Editorial: chinuahuas and laetrile, chelation therapy, and honey. Arch Intern Med 136:865–866
Gottrup F, Apelqvist J (2010) The challenge of using Randomised Trials in wound healing B.J.S. 97:303–304
Horkan L, Stansfield G, Miller M (2009) An Analysis of systemic Reviews undertaken on standardized advanced wound dressings in the last ten years. J wound Care 18:298–304
Gottrup F (2006) Evidence is a challenge in wound management. Int J Low extreme Wounds 5:74–75
Sultan MJ, Mccollum C (2009) Don’t wast money when dressing leg ulcers. Br J Surg 96:1099–1100
Balasubramnina SP, Weiner M, Alshameeri Z et al (2006) Standards of reporting of randomised controlled trials in general surgery. Can we do better? Ann Surg 244:663–667
Acknowledgements
Dr. Gadvi a scholarly surgeon working in Kenya with missionary zeal, who inspired this study. Dr. Rushad T. Udwadia, MS, FCPS, DNAB, FRCS Hon. Professor of Surgery J.J. Hospital, Consultant Surgeon Breach Candy Hospital, Parsee General Hospital, Mumbai who helped in this study. He declined the request to be a joint author as he felt his contribution did not merit it. Resident Surgeons in all the hospitals, who over several years, have helped in these trials with interest and perseverance. Ms. J. Bode, Ms. S. Konkrawala O.R. Superintendents, Parsee General Hospital who since 1991 have maintained gratis, a uniform product. Professor H.G. Doctor M.S., FRCSEd Emeritus Professor of Surgery J.J. Hospital, Senior Consultant Surgeon, Jain Clinic, Mumbai, who accepted the suggestion and used this dressing made at Parsee General Hospital for treatment of his patients with mesh exposed in the wound, documented, photographed and reported good results. Dr. Anita S. Bhaduri, M.D., Consultant Histopathologist, P.D.Hinduja Hospital for histopathology studies of spontaneous epithelialisation.
Funding
No source of funding
Conflict of interest
No conflict of interest
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Udwadia, T.E. Ghee and Honey Dressing for Infected Wounds. Indian J Surg 73, 278–283 (2011). https://doi.org/10.1007/s12262-011-0240-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12262-011-0240-7