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Evaluation of the antibacterial activity and treatment of acne with SiO2-ionized loess

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Abstract

SiO2-ionized loess was prepared from the reaction of loess and sodium hydroxide at 1,400°C for 2 h. The antibacterial activity of SiO2-ionized loess against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aerusinosa, and Propionobacterium acnes causing acne was examined by comparing the results against those of untreated loess, and treatment efficacy was examined for treating acne using soap containing SiO2-ionized loess. The minimum inhibitory concentration value of SiO2-ionized loess against S. aureus, P. aerusinosa, B. subtilis, E. coli, and P. acne was 10.0, 10.0, 2.5, 5.0, and 2.5 mg/mL, respectively. However, medium containing untreated loess had no antimicrobial activity. A treatment efficacy test revealed that acne symptoms decreased as the duration of using soap containing SiO2-ionized loess increased.

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Authors and Affiliations

  1. Research Institute of Biotechnology, Dongguk University, Seoul, 100-715, Korea

    Moon Young Yoon

  2. Department of Korean Medicine of International Hospital, Dongguk University, Il-san, 410-773, Korea

    Dong Il Kim

  3. Department of Medical Biotechnology, Dongguk University, Seoul, 100-715, Korea

    Jung-Keug Park

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  1. Moon Young Yoon
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  2. Dong Il Kim
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  3. Jung-Keug Park
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Correspondence to Jung-Keug Park.

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Yoon, M.Y., Kim, D.I. & Park, JK. Evaluation of the antibacterial activity and treatment of acne with SiO2-ionized loess. Biotechnol Bioproc E 15, 739–744 (2010). https://doi.org/10.1007/s12257-010-0028-9

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  • DOI: https://doi.org/10.1007/s12257-010-0028-9

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