Skip to main content
Log in

Primary non-Hodgkin’s lymphoma of the gingiva: a case report and review of the literature

  • case report
  • Published:
memo - Magazine of European Medical Oncology Aims and scope Submit manuscript

Summary

Up to 40 % of cases of non-Hodgkin’s lymphomas (NHL) occur with exclusive extranodal presentation, and involvement of the oral cavity is very rare. We report the case of a 40-year-old woman who presented with a gingival mass that was diagnosed as diffuse large B‑cell lymphoma (DLBCL). The patient was treated with chemoradiotherapy, thus, achieving a complete remission, and the patient is currently free of disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Scherfler S, Freier K, Seeberger R, Bacon C, Hoffmann J, Thiele OC. Cranio-maxillofacial non-Hodgkin’s lymphoma: clinical and histologicalp resentation. J Craniomaxillofac Surg. 2012;40(7):211–3.

    Article  Google Scholar 

  2. Patil AV, Deshpande RB, Kandalgaonkar SM, Gabhane MH. Diffuse large B‑celllymphoma (extranodal) of maxillary buccal vestibule. J Oral Maxillofac Pathol. 2015;19(2):270.

    PubMed  PubMed Central  Google Scholar 

  3. Vega F, Lin P, Medeiros LJ. Extranodal lymphomas of the head and neck. Ann Diagn Pathol. 2005;9(6):340–50.

    Article  Google Scholar 

  4. Kobler P, Borcic J, Filipovic Zore I, Nola M, Sertic D. Primary non-Hodgkin’s lymphoma of the oral cavity. Oral Oncol Extra. 2005;41:12–4.

    Article  Google Scholar 

  5. Kemp S, Gallagher G, Kabani S, Noonan V, O’Hara C. Oral non-Hodgkin’s lymphoma: Review of the literature and World Health Organization classification with reference to 40 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. Endod. 2008;105(2):194–201.

    Google Scholar 

  6. Angiero F, Stefani M, Crippa R. Primary non-Hodgkin’s lymphoma of the mandibular gingiva with maxillary gingival recurrence. Oral Oncol Extra. 2006;42:123–8.

    Article  Google Scholar 

  7. Etemad-Moghadam S, Tirgary F, Keshavarz S, Alaeddini M. Head and neck non-Hodgkin’s lymphoma: a 20-year demographicstudy of 381 cases. Int J Oral Maxillofac Surg. 2010;39(9):869–72.

    Article  CAS  Google Scholar 

  8. Owosho AA, Bilodeau EA, Surti U, Craig FE. Large B‑cell lymphoma of the base of the tongue and oral cavity: a practical approach to identifying prognostically important subtypes. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;118(3):338–47.

    Article  Google Scholar 

  9. Augustine D, Sekar B, Thiruneervannan R, Sundhar M, Reddy DV, Patil SG. Primary oral Non-Hodgkin’s Lymphoma: A clinic pathologic study with inmunohistochemical analysis. J Int Soc Prev Community Dent. 2014;4(Suppl 1):S68–71, Nov.

    Article  Google Scholar 

  10. Shah GH, Panwar SK, Chaturvedi PP, Kane SN. Isolated primary extranodal lymphoma of the oral cavity: A series of 15 cases and review of literature from a tertiary care cancer centre in India. Indian J Med Paediatr Oncol. 2011;32:76–81.

    Article  Google Scholar 

  11. Sehn LH, Scott DW, Chanabhai M, Berry B, Ruskova A, Berkahn L, Connors JM, Gascoyne RD. Impact of concordant and discordant bone marrow involvement on outcome in diffuse large B‑cell lymphoma treated with R‑CHOP. J Clin Oncol. 2011;29(11):1452.

    Article  Google Scholar 

  12. Imaizumi A, Kuribayashi A, Watanabe H, Ohbayashi N, Nakamura S, Sumi Y, Sano T, Kurabayashi T. Non-Hodgkin lymphoma involving the mandible: imaging findings. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(5):e33–9.

    Article  Google Scholar 

  13. Bugshan A, Kassolis J, Basile J. Primary Diffuse Large B‑Cell Lymphoma of the Mandible: Case Report and Review of the Literature. Case Rep Oncol. 2015;24;8(3):451–5.

    Article  Google Scholar 

  14. Abbaszadeh H, Mohtasham N, Pazouki M, Babakoohi S. Primary diffuse large B‑cell lymphoma of the mandible: A case report. J Oral Maxillofac Surg Med Pathol. 2014;26:98–100.

    Article  Google Scholar 

  15. Pazoki A, Jansisyanont P, Ord RA. Primary non-Hodgkin’s lymphoma of the jaws: Report of 4 cases and review of the literature. J Oral Maxillofac Surg. 2003;61(1):112–7, Jan.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ilson Sepúlveda.

Ethics declarations

Conflict of interest

I. Sepúlveda, M. Schorwer, E. Platin, M. Yañez, and F. Fredes declare that they have no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sepúlveda, I., Schorwer, M., Platin, E. et al. Primary non-Hodgkin’s lymphoma of the gingiva: a case report and review of the literature. memo 9, 183–186 (2016). https://doi.org/10.1007/s12254-016-0289-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12254-016-0289-x

Keywords

Navigation