Abstract
The first biologically interactive albumin-bound paclitaxel in a nanometer particle is described in a patient with metastatic pancreatic cancer. The aim of this report is to underline the efficacy and tolerability of the new chemotherapy option. A 78-year-old male patient with metastatic pancreatic cancer received third-line nab-paclitaxel monotherapy in September 2011 until October 2012 in weekly or bi-weekly intervals. A partial response was detected by computed tomography scan 2 months after start of therapy, and this was confirmed after 5 and 8 months. While on therapy, 30 applications of nab-paclitaxel monotherapy allowed the patient to experience a solid partial response and a progression-free survival of 12 months. During treatment, the patient did not develop any side effects and experienced excellent quality of life. This experience emphasizes the potential clinical utility of nab-paclitaxel chemotherapy in the setting of metastatic pancreatic cancer.
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Acknowledgments
The author, Ferdinand Haslbauer, acquired data, wrote the clinical part of the manuscript, revised the data, critically reviewed the manuscript, and approved the final version for submission. The author thanks Michaela Gruber for editorial support.
Conflict of interest
Ferdinand Haslbauer received financial support from Celgene Austria.
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Haslbauer, F. Case report of nab-paclitaxel in metastatic pancreatic cancer. memo 7, 39–42 (2014). https://doi.org/10.1007/s12254-014-0138-8
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DOI: https://doi.org/10.1007/s12254-014-0138-8