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Oesophageal cancer – ASCO 2009

  • ASCO 2009 - Short Review
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memo - Magazine of European Medical Oncology Aims and scope Submit manuscript

Neoadjuvant chemoradiation therapy followed by the surgical resection of residual disease has become the most common treatment strategy for locally advanced disease despite the lack of a convincing phase III trial supporting this treatment approach. This year’s ASCO meeting saw the presentation of the first results of neoadjuvant chemoradiotherapy replacing old drugs such as Cisplatin by newer substances such as Oxaliplatin, Docetaxel and the integration of biological agents into the preoperative approach.

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References

  1. Leichman L, Goldman BH, Benedetti JK, Billiningsley KG, Thomas CR, Iqbal S, Lenz H, Blanke C, Gold PJ and Corless CL (2009). Oxaliplatin (OXP) plus protraced infusion 5-fluorouracil (PIFU) and external beam radiation (EBRT) prior to surgery (S) for potentially curable esophageal adenocarcinoma (EA): a southwest oncology group (SWOG) phase Iitrial with molecular correlates (S0356). J Clin Oncol 27: 205s(#4513)

    Google Scholar 

  2. Pasini F, de Manzoni G, Stievano L, Grandinetti A, Maluta S, Capirci C, Durante E, Bonetti A, Zanoni A and Cordiano C (2009). Effect of neoadjuvant combined modality therapy with weekly docetaxel (D) and cisplatin (P), 5-fluorouracil (5-FU) continuous infusion (c.i.), and concurrent radiotherapy (RT) on pathological response rate in esophageal cancers (EC): a phase II study. J Clin Oncol 27: 213s(#4548)

    Google Scholar 

  3. De Vita F., Orditura M, Innocente R, Vecchione L, Pinto C, Chiarion Sileni V, Martinelli E, Ruol A, Catalano G and Ciardiello F (2009). A multicenter phase II study of induction CT with FOLFOX-4 and cetuximab followed by RT and cetuximab in locally advanced esophageal cancer (LAEC). J Clin Oncol 27: 213s(#4546)

    Google Scholar 

  4. Agarwala AK, Hanna N, Mc Collum A, Bechar N, Di Maio M, Yu M, Tong Y, Becerra CR and Choy H (2009). Preoperative cetuximab and radiation (XRT) fpr patients (pts) with surgically resectable esophageal and gastroesophageal junction (GEJ) carcinomas: a pilot study from the Hoosier Oncology Group and the university of Texas Southwestern. J Clin Oncol 27: 216s(#4557)

    Article  Google Scholar 

  5. Ruhstaller T, Pless M, Schuller JC, Kranzbühler H, Moos R, Moosmann P, Rauch D, Montemurro M, Schneider PM and Hess V (2009). Cetuximab in combination with chemoradiotherapy prior to surgery in patients with resectable, locally advanced esophageal carcinoma: a prospective multicenter phase Ib-Iitrial of the Swiss Group for Clinical Cancer Research (SAKK 75/06). J Clin Oncol 27: 219s(#4570)

    Google Scholar 

  6. Ilson D, Bains M, Rizk N, Rusch V, Flores R, Park B, Shah M, Kelsen D, Miron B and Goodman K (2009). Phase Iitrial of preoperative bevacizumab (Bev), irinotecan (I), cisplatin ©, and radiation (RT) in esophageal adenocarcinoma: preliminary safety analysis. J Clin Oncol 27: 220s(#4573)

    Google Scholar 

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Correspondence to Wolfgang Eisterer MD.

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Eisterer, W. Oesophageal cancer – ASCO 2009. memo 2, 221–222 (2009). https://doi.org/10.1007/s12254-009-0167-x

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  • DOI: https://doi.org/10.1007/s12254-009-0167-x

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