Pathology & Oncology Research

, Volume 25, Issue 2, pp 825–826 | Cite as

Promoter Mutation Analysis of ALDOA Gene in Solid Tumors and Acute Leukemias

  • Hyun Ji Son
  • Eun Ji Choi
  • Nam Jin YooEmail author
  • Sug Hyung LeeEmail author
Letter to the Editor



This work was supported by a grant from National Research Foundation of Korea (2016R1D1A1B01007490).


  1. 1.
    Chang YC, Yang YC, Tien CP, Yang CJ, Hsiao M (2018) Roles of aldolase family genes in human cancers and diseases. Trends Endocrinol Metab 29:549–559CrossRefGoogle Scholar
  2. 2.
    Ji S, Zhang B, Liu J, Qin Y, Liang C, Shi S, Jin K, Liang D, Xu W, Xu H, Wang W, Wu C, Liu L, Liu C, Xu J, Ni Q, Yu X (2016) ALDOA functions as an oncogene in the highly metastatic pancreatic cancer. Cancer Lett 374:127–135CrossRefGoogle Scholar
  3. 3.
    Rheinbay E, Parasuraman P, Grimsby J, Tiao G, Engreitz JM, Kim J, Lawrence MS, Taylor-Weiner A, Rodriguez-Cuevas S, Rosenberg M, Hess J, Stewart C, Maruvka YE, Stojanov P, Cortes ML, Seepo S, Cibulskis C, Tracy A, Pugh TJ, Lee J, Zheng Z, Ellisen LW, Iafrate AJ, Boehm JS, Gabriel SB, Meyerson M, Golub TR, Baselga J, Hidalgo-Miranda A, Shioda T, Bernards A, Lander ES, Getz G (2017) Recurrent and functional regulatory mutations in breast cancer. Nature 547:55–60CrossRefGoogle Scholar
  4. 4.
    Heng J, Guo X, Wu W, Wang Y, Li G, Chen M, Peng L, Wang S, Dai L, Tang L, Wang J (2017) Integrated analysis of promoter mutation, methylation and expression of AKT1 gene in Chinese breast cancer patients. PLoS One 12:e0174022CrossRefGoogle Scholar
  5. 5.
    Yoo NJ, Kim HR, Kim YR, An CH, Lee SH (2012) Somatic mutations of the KEAP1 gene in common solid cancers. Histopathology 60:943–952CrossRefGoogle Scholar

Copyright information

© Arányi Lajos Foundation 2018

Authors and Affiliations

  1. 1.Department of Pathology, College of MedicineThe Catholic University of KoreaSeoulSouth Korea

Personalised recommendations