References
Raheja R, Gandhi R (2016) FXR1: linking cellular quiescence, immune genes and cancer. Cell Cycle 15:2695–2696
Vasudevan S, Steitz JA (2007) AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell 128:1105–1118
Qian J, Hassanein M, Hoeksema MD, Harris BK, Zou Y, Chen H, Lu P, Eisenberg R, Wang J, Espinosa A, Ji X, Harris FT, Rahman SM, Massion PP (2015) The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers. Proc Natl Acad Sci U S A 112:3469–3474
Imai K, Yamamoto H (2008) Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. Carcinogenesis 29:673–680
Oh HR, An CH, Yoo NJ, Lee SH (2015) Frameshift mutations of MUC15 gene in gastric and its regional heterogeneity in gastric and colorectal cancers. Pathol Oncol Res 21:713–718
Marusyk A, Almendro V, Polyak K (2012) Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer 12:323–334
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This work was supported by a grant from National Research Foundation of Korea (2013R1A1A2062603).
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Yun Sol Jo and Sung Soo Kim contributed equally to this work.
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Jo, Y.S., Kim, S.S., Kim, M.S. et al. Frameshift Mutation of FXR1 Encoding a RNA-Binding Protein in Gastric and Colorectal Cancers with Microsatellite Instability. Pathol. Oncol. Res. 23, 453–454 (2017). https://doi.org/10.1007/s12253-016-0177-z
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DOI: https://doi.org/10.1007/s12253-016-0177-z