References
Alessi DR, Sakamoto K, Bayascas JR (2006) LKB1-dependent signaling pathways. Transcription 4:29–33
Hemminki A, Tomlinson I, Markie D, Järvinen H, Sistonen P, Björkqvist AM, Knuutila S, Salovaara R, Bodmer W, Shibata D, de la Chapelle A, Aaltonen LA (1997) Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 15:87–90
Sanchez-Cespedes M (2007) A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome. Oncogene 26:7825–7832
Mehellou Y, Alessi DR, Macartney TJ, Szklarz M, Knapp S, Elkins JM (2013) Structural insights into the activation of MST3 by MO25. Biochem Biophys Res Commun 431:604–609
Ling P, Lu TJ, Yuan CJ, Lai MD (2008) Biosignaling of mammalian Ste20-related kinases. Cell Signal 20:1237–1247
Imai K (2008) Yamamoto H (2008) carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. Carcinogenesis 29:673–680
Yoo NJ, Kim HR, Kim YR, An CH (2012) Lee SH (2012) Somatic mutations of the KEAP1 gene in common solid cancers. Histopathology 60:943–952
Je EM, Kim MR, Min KO, Yoo NJ, Lee SH (2012) Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors. Int J Cancer 131:E1044–E1047
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz Jr LA, Kinzler KW (2013) Cancer genome landscapes. Science 339:1546–1558
Marusyk A, Almendro V, Polyak K (2012) Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer 12:323–334
Acknowledgments
This work was supported by a grant from National Research Foundation of Korea (2012R1A5A2047939).
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Mi Ryoung Choi and Chang Hyeok An contributed equally to this work.
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Choi, M.R., An, C.H., Yoo, N.J. et al. Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers. Pathol. Oncol. Res. 22, 225–226 (2016). https://doi.org/10.1007/s12253-015-9973-0
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DOI: https://doi.org/10.1007/s12253-015-9973-0