Abstract
Basal cell carcinoma, the most common skin cancer, has several clinical and histopathological variants, with its most common form being nodular basal cell carcinoma. Fibrioepithelioma of Pinkus is considered as an unusual variant of basal cell carcinoma by some authors while others consider it to be a benign analogue of basal cell carcinoma. We present a rare case of fibroepithelioma of Pinkus in continuity with a nodular basal cell carcinoma, a finding that supports the classification of fibroepithelioma of Pinkus as a variant of basal cell carcinoma.
References
Bath-Hextall F, Bong J, Perkins W et al (2004) Interventions for basal cell carcinoma of the skin: systematic review. BMJ 329:705
Wong CS, Strange RC, Lear JT (2003) Basal cell carcinoma. BMJ 327:794–8
Crowson AN (2006) Basal cell carcinoma: biology, morphology and clinical implications. Mod Pathol 19:S127–47
Brooke RC (2005) Basal cell carcinoma. Clin Med 5:551–4
Misago N, Suzuki Y, Miura Y et al (2004) Giant polypoid basal cell carcinoma with features of fibroepithelioma of Pinkus and extensive cornification. Eur J Dermatol 14:272–5
Gellin GA, Bender B (1966) Giant premalignant fibroepithelioma. Arch Dermatol 94:70–3
Pinkus H (1953) Premalignant fibroepithelial tumors of skin. Arch Dermatol Syphilol 67:598–615
Zalaudek I, Ferrara G, Broganelli P et al (2006) Dermoscopy patterns of fibroepithelioma of pinkus. Arch Dermatol 142:1318–22
Bowen AR, LeBoit PE (2005) Fibroepithelioma of pinkus is a fenestrated trichoblastoma. Am J Dermatopathol 27:149–54
Katona TM, Ravis SM, Perkins SM et al (2007) Expression of androgen receptor by fibroepithelioma of Pinkus: evidence supporting classification as a basal cell carcinoma variant? Am J Dermatopathol 29:7–12
Stern JB, Haupt HM, Smith RR (1994) Fibroepithelioma of Pinkus: eccrine duct spread of basal cell carcinoma. Am J Dermatopathol 16:585–7
Schulz T, Hartschuh W (1997) Merkel cells are absent in basal cell carcinomas but frequently found in trichoblastomas. An immunohistochemical study. J Cutan Pathol 24:14–24
Ackerman AB, Gottlieb GJ (2005) Fibroepithelial tumor of Pinkus is trichoblastic (basal-cell) carcinoma. Am J Dermatopathol 27:155–9
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Ioannidis, O., Papaemmanuil, S., Kakoutis, E. et al. Fibroepithelioma of Pinkus in Continuity with Nodular Basal Cell Carcinoma: Supporting Evidence of the Malignant Nature of the Disease. Pathol. Oncol. Res. 17, 155–157 (2011). https://doi.org/10.1007/s12253-010-9284-4
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DOI: https://doi.org/10.1007/s12253-010-9284-4