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Orbital Tumour as Initial Manifestation of Acute Myeloid Leukemia: Granulocytic Sarcoma: Case Report

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Pathology & Oncology Research


We report orbital involvement as an initial manifestation of acute myeloid leukemia in a 57-year-old woman. The patient presented with painful proptosis and limited ocular motility. Orbital computed tomography revealed bilateral homogeneous masses. Orbital biopsy was performed on the right side; and histopathology disclosed a myelocytic tumour. Despite treatment using irradiation and chemotherapy, the patient died eleven months after presentation. There appear to be only a few previous reports of acute myeloid leukemia cases presenting with orbital involvement, and most cases occurred in children. This very rare condition has a poor survival prognosis, even with radiation treatment and chemotherapy.

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Correspondence to Erika Maka.

Additional information

This case was presented at The European Society of Ophthalmic Plastic and Reconstructive Surgery (ESOPRS) 2005 Annual Meeting, held in Crete, Greece.

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Maka, E., Lukáts, O., Tóth, J. et al. Orbital Tumour as Initial Manifestation of Acute Myeloid Leukemia: Granulocytic Sarcoma: Case Report. Pathol. Oncol. Res. 14, 209–211 (2008).

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