Skip to main content

Advertisement

Log in

Orbital Tumour as Initial Manifestation of Acute Myeloid Leukemia: Granulocytic Sarcoma: Case Report

  • Brief Communication
  • Published:
Pathology & Oncology Research

Abstract

We report orbital involvement as an initial manifestation of acute myeloid leukemia in a 57-year-old woman. The patient presented with painful proptosis and limited ocular motility. Orbital computed tomography revealed bilateral homogeneous masses. Orbital biopsy was performed on the right side; and histopathology disclosed a myelocytic tumour. Despite treatment using irradiation and chemotherapy, the patient died eleven months after presentation. There appear to be only a few previous reports of acute myeloid leukemia cases presenting with orbital involvement, and most cases occurred in children. This very rare condition has a poor survival prognosis, even with radiation treatment and chemotherapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Zimmerman LE, Font RL (1975) Ophthalmologic manifestations of granulocytic sarcoma (myeloid sarcoma or chloroma). Am J Ophthalmol 80:975–989

    PubMed  CAS  Google Scholar 

  2. Bhattacharjee K, Bhattacharjee H, Das D, Babu K, Mahesh L, Krishnakumar S, Biswas J (2003) Chloroma of the orbit in a non-leukemic adult: a case report. Orbit 22:293–297

    Article  PubMed  Google Scholar 

  3. Kincaid MC, Green WR (1983) Ocular and Orbital Involvement in Leukemia. Surv Ophthalmol 27:211–232

    Article  PubMed  CAS  Google Scholar 

  4. Padillo D, Mencía E, Gutiérrez E, Martínez MA (1999) Orbital granulocytic sarcoma in a myelodysplastic syndrome. Orbit 18:287–290

    Article  PubMed  Google Scholar 

  5. Stockl FA, Dolmetsch AM, Saornil MA, Font RL, Burnier MN (1997) Orbital granulocytic sarcoma. Br J Ophthalmol 81:1084–1088

    Article  PubMed  CAS  Google Scholar 

  6. Watkins LM, Remulla HD, Rubin PAD (1997) Orbital granulocytic sarcoma in an elderly patient. Am J Ophthalmol 123:854–856

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Erika Maka.

Additional information

This case was presented at The European Society of Ophthalmic Plastic and Reconstructive Surgery (ESOPRS) 2005 Annual Meeting, held in Crete, Greece.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Maka, E., Lukáts, O., Tóth, J. et al. Orbital Tumour as Initial Manifestation of Acute Myeloid Leukemia: Granulocytic Sarcoma: Case Report. Pathol. Oncol. Res. 14, 209–211 (2008). https://doi.org/10.1007/s12253-008-9028-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12253-008-9028-x

Keywords

Navigation