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References
Cox AL, Netski DM, Mosbruger T, Sherman SG, Strathdee S, Ompad D, Vlahov D, Chien D, Shyamala V, Ray S (2005) Prospective evaluation of community-acquired acute-phase hepatitis C virus infection. Clin Infect Dis 40:951–958
Cui Y, Jia J (2013) Update on epidemiology of hepatitis B and C in China. J Gastroenterol Hepatol 28:7–10
Fu Y, Xia W, Wang Y, Tian L, Phbus OG, Lu L, Nelson K (2010) The seroprevalence of hepatitis C virus (HCV) among 559,890 first-time volunteer blood donors in China reflects regional heterogeneity in HCV prevalence and changes in blood donor recruitment models. Transfusion 50:1505–1511
Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, Gascuel O (2010) New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol 59:307–321
Hoofnagle JH (1997) Hepatitis C: the clinical spectrum of disease. Hepatology 26:15S–20S
Karmochkine M, Carrat F, Dos Santos O, Cacoub P, Raguin G (2006) A case-control study of risk factors for hepatitis C infection in patients with unexplained routes of infection. J Viral Hepat 13:775–782
Kiyosawa K, Tanaka E, Sodeyama T, Yoshizawa K, Yabu K, Furuta K, Imai H, Nakano Y, Usuda S, Uemura K, Furuta S, Watanabe Y, Watanabe J, Fukuda Y, The South Kiso Hepatitis Study Group (1994) Transmission of hepatitis C in an isolated area in Japan: community-acquired infection. Gastroenterology 106:1596–1602
Lauer GM, Walker BD (2001) Hepatitis C virus infection. N Engl J Med 345:41–52
Li XM, Qiu RX, Song CH, Huang QH, Wang XD, Hu ZT, He XZ, Ye XY, Huang XG, Zheng FF, Lin GX (2017) Genotype and genetic variation of HCV infections with low-risk factors in Putian coastal regions, China. Epidemiol Infect 145:3385–3397
Lu L, Tong W, Gu L, Li C, Tee KK, Chen G (2013) The current hepatitis C virus prevalence in China may have resulted mainly from an officially encouraged plasma campaign in the 1990s: a coalescence inference with genetic sequences. J Virol 87:12041–12050
Lu L, Wang M, Xia W, Tian L, Xu R, Li C, Wang J, Rong X, Xiong H, Huang K, Huang J, Nakano T, Bennett P, Zhang Y, Zhang L, Fu Y (2014) Migration patterns of hepatitis C virus in china characterized for five major subtypes based on samples from 411 volunteer blood donors from 17 provinces and municipalities. J Virol 88:7120–7129
Mariano A, Mele A, Tosti ME, Parlato A, Gallo G, Ragni P, Zotti C, Lopalco P, Pompa MG, Graziani G, Stroffolini T (2004) Role of beauty treatment in the spread of parenterally transmitted hepatitis viruses in Italy. J Med Virol 74:216–220
Mosley JW, Operskalski EA, Tobler LH, Andrews WW, Phelps B, Dockter J, Giachetti C, Busch MP (2005) Viral and host factors in early hepatitis C virus infection. Hepatology 42:86–92
Peng J, Lu Y, Liu W, Zhu Y, Yan X, Wang X, Wang Y, Liu W, Sun Z (2015) Genotype distribution and molecular epidemiology of hepatitis C virus in Hubei Central China. PLoS ONE 10:e0137059
Villano SA, Vlahov D, Nelson KE, Cohn S, Thomas DL (1999) Persistence of viremia and the importance of long-term follow-up after acute hepatitis C infection. Hepatology 29:908–914
Yin W, Huang C, Qiu F, Liu L, Wang F, Zhou J, Zhang Y, Bi S (2015) Risk factors of hepatitis C virus transmission and genotype distribution in former blood donors from Chinese rural area. BMC Public Health 15:184
Acknowledgements
This study was supported by the National Natural Science Foundation of China (Grants 81861138003 and 81672057).
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LYZ and YZZ designed the study. XCQ and LHZ performed the experiments. LHZ and LYZ collected clinical data in this study. XCQ, AP and YZZ analyzed the data. XCQ, AP and YZZ drafted the manuscript. All authors interpreted the results and approved the final manuscript.
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The investigation was reviewed and approved by the Ethics Committees of the Fourth Hospital of Harbin Medical University and the Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention. Additional informed consent was obtained from all patients for which identifying information is included in this article.
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Qin, XC., Zhong, LH., Zhu, LY. et al. Hepatitis C Virus Infection Caused by Infrequent Exposure in China Should Be of Concern. Virol. Sin. 35, 481–485 (2020). https://doi.org/10.1007/s12250-019-00191-4
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DOI: https://doi.org/10.1007/s12250-019-00191-4