Advertisement

Virologica Sinica

, Volume 33, Issue 6, pp 561–564 | Cite as

Mink Circovirus Can Infect Minks, Foxes and Raccoon Dogs

  • Yanling Yang
  • Yuening Cheng
  • Nan Li
  • Shipeng Cheng
  • Li Guo
  • Yucheng Zhou
  • Haiwei Zhang
  • Xinyuan Zhang
  • Linzhu RenEmail author
Letter
  • 122 Downloads

Dear Editor,

Mink circovirus (MiCV), which is clustered in the genus Circovirus of the family Circoviridae, was first described in minks from farms in Dalian, China in 2013 (Lian et al.2014). The complete single-stranded circular genome of the virus is 1,753 nucleotides long and contains two major open reading frames (ORFs), designated ORF1 (Rep gene) and ORF2 (Cap gene) (Lian et al.2014; Ge et al.2018). Sequence analysis has shown that MiCV is most closely related to mammalian circoviruses, such as bat circovirus (BatCV), porcine circovirus (PCV), and dog circovirus (dogCV) (Ge et al.2018). Epidemiological investigations have revealed that the mink circovirus is very prevalent in China, with a positive rate of up to 54.6% (101/185) on some mink farms in China (Lian et al.2014; Wang et al.2015; Ge et al.2018). The virus is found in the liver, digestive tract, and fecal specimens of minks, with diarrhea as the main clinical sign (Lian et al.2014).

Minks, foxes and raccoon dogs are...

Notes

Acknowledgements

This work was financially supported by the National Key Research and Development Program of China (No. 2017YFD0500103), the National Natural Science Foundation of China (No. 31772747), the Science and Technology Development Project of Jilin Province (No. 20170623043TC), the Program for JLU Science and Technology Innovative Research Team (JLUSTIRT, No. 2017TD-28), and the Fundamental Research Funds for the Central Universities.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they do not have any conflict of interest.

Animal and Human Rights Statement

All animal experiments were approved by the Animal Care and Ethics Committee of Jilin University (Changchun, China).

Supplementary material

12250_2018_59_MOESM1_ESM.pdf (528 kb)
Supplementary material 1 (PDF 528 kb)

References

  1. Cha S, Song E, Kang M, Wei B, Seo H, Roh J, Yoon R, Moon O, Jang H (2014) Prevalence of duck circovirus infection of subclinical pekin ducks in South Korea. J Vet Med Sci 76:597–599CrossRefGoogle Scholar
  2. Ge J, Gu S, Cui X, Zhao L, Ma D, Shi Y, Wang Y, Lu T, Chen H (2018) Genomic characterization of circoviruses associated with acute gastroenteritis in minks in northeastern China. Arch Virol 163:2727–2735CrossRefGoogle Scholar
  3. Gillespie J, Opriessnig T, Meng XJ, Pelzer K, Buechner-Maxwell V (2009) Porcine circovirus type 2 and porcine circovirus-associated disease. J Vet Intern Med 23:1151–1163CrossRefGoogle Scholar
  4. Hu Y, Zhan Y, Wang D, Xie X, Liu T, Liu W, Wang N, Deng Z, Lei H, Yang Y, Wang A (2017) Evidence of natural co-infection with PCV2b subtypes in vivo. Arch Virol 162:2015–2020CrossRefGoogle Scholar
  5. Lian H, Liu Y, Li N, Wang YY, Zhang SF, Hu RL (2014) Novel circovirus from Mink, China. Emerg Infect Dis 20:1548–1550CrossRefGoogle Scholar
  6. Meng XJ (2013) Porcine circovirus type 2 (PCV2): pathogenesis and interaction with the immune system. Annu Rev Anim Biosci 1:43–64CrossRefGoogle Scholar
  7. Opriessnig T, Halbur PG (2012) Concurrent infections are important for expression of porcine circovirus associated disease. Virus Res 164:20–32CrossRefGoogle Scholar
  8. Ren L, Chen X, Ouyang H (2016) Interactions of porcine circovirus 2 with its hosts. Virus Genes 52:437–444CrossRefGoogle Scholar
  9. Shulman LM, Davidson I (2017) Viruses with circular single-stranded DNA genomes are everywhere! Annu Rev Virol 4:159–180CrossRefGoogle Scholar
  10. Sun J, Huang L, Wei Y, Wang Y, Chen D, Du W, Wu H, Liu C (2015) Prevalence of emerging porcine parvoviruses and their co-infections with porcine circovirus type 2 in China. Arch Virol 160:1339–1344CrossRefGoogle Scholar
  11. Wang Y, Liu Y, Lian H, Li N, Zhang L (2015) Molecular epidemiology of mink circovirus. Chin J Vet Med 51:6–8Google Scholar
  12. Yang Y, Shi R, She R, Mao J, Zhao Y, Du F, Liu C, Liu J, Cheng M, Zhu R, Li W, Wang X, Soomro MH (2015) Fatal disease associated with Swine Hepatitis E virus and Porcine circovirus 2 co-infection in four weaned pigs in China. BMC Vet Res 11:77CrossRefGoogle Scholar
  13. Yi J, Liu C (2010) Molecular characterization of porcine circovirus 2 isolated from diseased pigs co-infected with porcine reproductive and respiratory syndrome virus. Virol J 7:286CrossRefGoogle Scholar
  14. Zhai SL, Chen SN, Wei ZZ, Zhang JW, Huang L, Lin T, Yue C, Ran DL, Yuan SS, Wei WK, Long JX (2011) Co-existence of multiple strains of porcine circovirus type 2 in the same pig from China. Virol J 8:517CrossRefGoogle Scholar
  15. Zhang HL, Yan XJ, Chai XL, Wu W, Yi L, Luo GL, Tian HY, Shao XQ, Wang FX (2007) Establishment and application of pcr for detection of mink enter itis virus. Spec Wild Econ Anim Plant Res 29:1–3 (in Chinese) Google Scholar

Copyright information

© Wuhan Institute of Virology, CAS and Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Wild Economic Animals and PlantsChinese Academy of Agricultural SciencesChangchunChina
  2. 2.Jilin Provincial Key Laboratory of Animal Embryo Engineering, College of Animal SciencesJilin UniversityChangchunChina
  3. 3.Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Military Veterinary InstituteAcademy of Military Medical SciencesChangchunChina

Personalised recommendations