Virologica Sinica

, Volume 33, Issue 6, pp 561–564 | Cite as

Mink Circovirus Can Infect Minks, Foxes and Raccoon Dogs

  • Yanling Yang
  • Yuening Cheng
  • Nan Li
  • Shipeng Cheng
  • Li Guo
  • Yucheng Zhou
  • Haiwei Zhang
  • Xinyuan Zhang
  • Linzhu RenEmail author

Dear Editor,

Mink circovirus (MiCV), which is clustered in the genus Circovirus of the family Circoviridae, was first described in minks from farms in Dalian, China in 2013 (Lian et al.2014). The complete single-stranded circular genome of the virus is 1,753 nucleotides long and contains two major open reading frames (ORFs), designated ORF1 (Rep gene) and ORF2 (Cap gene) (Lian et al.2014; Ge et al.2018). Sequence analysis has shown that MiCV is most closely related to mammalian circoviruses, such as bat circovirus (BatCV), porcine circovirus (PCV), and dog circovirus (dogCV) (Ge et al.2018). Epidemiological investigations have revealed that the mink circovirus is very prevalent in China, with a positive rate of up to 54.6% (101/185) on some mink farms in China (Lian et al.2014; Wang et al.2015; Ge et al.2018). The virus is found in the liver, digestive tract, and fecal specimens of minks, with diarrhea as the main clinical sign (Lian et al.2014).

Minks, foxes and raccoon dogs are...



This work was financially supported by the National Key Research and Development Program of China (No. 2017YFD0500103), the National Natural Science Foundation of China (No. 31772747), the Science and Technology Development Project of Jilin Province (No. 20170623043TC), the Program for JLU Science and Technology Innovative Research Team (JLUSTIRT, No. 2017TD-28), and the Fundamental Research Funds for the Central Universities.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they do not have any conflict of interest.

Animal and Human Rights Statement

All animal experiments were approved by the Animal Care and Ethics Committee of Jilin University (Changchun, China).

Supplementary material

12250_2018_59_MOESM1_ESM.pdf (528 kb)
Supplementary material 1 (PDF 528 kb)


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Copyright information

© Wuhan Institute of Virology, CAS and Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Wild Economic Animals and PlantsChinese Academy of Agricultural SciencesChangchunChina
  2. 2.Jilin Provincial Key Laboratory of Animal Embryo Engineering, College of Animal SciencesJilin UniversityChangchunChina
  3. 3.Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Military Veterinary InstituteAcademy of Military Medical SciencesChangchunChina

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