Mink Circovirus Can Infect Minks, Foxes and Raccoon Dogs
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Mink circovirus (MiCV), which is clustered in the genus Circovirus of the family Circoviridae, was first described in minks from farms in Dalian, China in 2013 (Lian et al.2014). The complete single-stranded circular genome of the virus is 1,753 nucleotides long and contains two major open reading frames (ORFs), designated ORF1 (Rep gene) and ORF2 (Cap gene) (Lian et al.2014; Ge et al.2018). Sequence analysis has shown that MiCV is most closely related to mammalian circoviruses, such as bat circovirus (BatCV), porcine circovirus (PCV), and dog circovirus (dogCV) (Ge et al.2018). Epidemiological investigations have revealed that the mink circovirus is very prevalent in China, with a positive rate of up to 54.6% (101/185) on some mink farms in China (Lian et al.2014; Wang et al.2015; Ge et al.2018). The virus is found in the liver, digestive tract, and fecal specimens of minks, with diarrhea as the main clinical sign (Lian et al.2014).
Minks, foxes and raccoon dogs are...
This work was financially supported by the National Key Research and Development Program of China (No. 2017YFD0500103), the National Natural Science Foundation of China (No. 31772747), the Science and Technology Development Project of Jilin Province (No. 20170623043TC), the Program for JLU Science and Technology Innovative Research Team (JLUSTIRT, No. 2017TD-28), and the Fundamental Research Funds for the Central Universities.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they do not have any conflict of interest.
Animal and Human Rights Statement
All animal experiments were approved by the Animal Care and Ethics Committee of Jilin University (Changchun, China).
- Wang Y, Liu Y, Lian H, Li N, Zhang L (2015) Molecular epidemiology of mink circovirus. Chin J Vet Med 51:6–8Google Scholar
- Zhang HL, Yan XJ, Chai XL, Wu W, Yi L, Luo GL, Tian HY, Shao XQ, Wang FX (2007) Establishment and application of pcr for detection of mink enter itis virus. Spec Wild Econ Anim Plant Res 29:1–3 (in Chinese) Google Scholar