Molecular Epidemiology of Porcine Circovirus Type 3 Infection in Swine Herds in China
Porcine circovirus type 3 (PCV3) is a new-emerging circovirus belonging to the genus Circovirus in the family Circoviridae in which PCV type 1 (PCV1) and PCV type 2 (PCV2) were well documented (Palinski et al.2017). PCV1 is a cell culture-derived virus and is considered to be nonpathogenic for swine, whereas PCV2 is the primary etiological agent of porcine circovirus-associated diseases (PCVAD) that causes severe economic losses in the swine industry worldwide (Zhai et al.2014). PCV3 was firstly reported in the United States of America in 2016 (Palinski et al.2017). After that, PCV3 has been detected in Poland, South Korea, Italy, Brazil, United Kingdom, and China, and was reported to be associated with porcine dermatitis and nephropathy syndrome, congenital tremors, reproductive failure, and multi-systemic inflammation (Kwon et al.2017; Li and Tian 2017; Palinski et al.2017; Stadejek et al.2017; Zheng et al.2017). The first case of PCV3 in China was reported in Guangdong...
This work was supported by grant from National Key Research and Development Program (2016YFD0500703), Major science and technology projects in Henan Province (171100110200), and Luoyang HeLuo Talent Plan (to Dr. Kegong Tian).
Compliance with Ethical Standards
Conflict of interest
The authors declare that they do not have any conflict of interest.
Animal and Human Rights Statement
This study was approved by the Animal Care and Ethics Committee of National Research Center for Veterinary Medicine with IACUC Number 2018054.
- Li X, Galliher-Beckley A, Pappan L, Trible B, Kerrigan M, Beck A, Hesse R, Blecha F, Nietfeld JC, Rowland RR, Shi J (2014) Comparison of host immune responses to homologous and heterologous type II porcine reproductive and respiratory syndrome virus (PRRSV) challenge in vaccinated and unvaccinated pigs. Biomed Res Int 2014:416727PubMedPubMedCentralGoogle Scholar