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Virologica Sinica

, Volume 33, Issue 3, pp 287–290 | Cite as

N-Terminal Myristoylated VP5 is Required for Penetrating Cell Membrane and Promoting Infectivity in Aquareoviruses

Letter
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Notes

Acknowledgements

This work is supported in part by grants from the National Natural Science Foundation of China (31672693, 31372565, 31172434).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Animal and Human Rights Statement

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

  1. Agosto MA, Ivanovic T, Nibert ML (2006) Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane. Proc Natl Acad Sci USA 103:16496–16501CrossRefPubMedPubMedCentralGoogle Scholar
  2. Agosto MA, Myers KS, Ivanovic T, Nibert ML (2008) A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration. Proc Natl Acad Sci USA 105:10571–10576CrossRefPubMedPubMedCentralGoogle Scholar
  3. Attoui H, Fang Q, Mohd Jaafar F, Cantaloube JF, Biagini P, de Micco P, de Lamballerie X (2002) Common evolutionary origin of aquareoviruses and orthoreoviruses revealed by genome characterization of Golden shiner reovirus, Grass carp reovirus, Striped bass reovirus and golden ide reovirus (genus Aquareovirus, family Reoviridae). J Gen Virol 83:1941–1951CrossRefPubMedGoogle Scholar
  4. Chen Q, Zhang J, Zhang F, Guo H, Fang Q (2016) Identification and characterization of two cleavage fragments from the Aquareovirus nonstructural protein NS80. Virol Sin 31:314–323CrossRefPubMedGoogle Scholar
  5. Cheng L, Fang Q, Shah S, Atanasov IC, Zhou ZH (2008) Subnanometer-resolution structures of the grass carp reovirus core and virion. J Mol Biol 382:213–222CrossRefPubMedPubMedCentralGoogle Scholar
  6. Cheng L, Zhu J, Hui WH, Zhang X, Honig B, Fang Q, Zhou ZH (2010) Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics. J Mol Biol 397:852–863CrossRefPubMedGoogle Scholar
  7. Fang Q, Attoui H, Cantaloube JF, Biagini P, Zhu Z, de Micco P, de Lamballerie X (2000) Sequence of genome segments 1, 2, and 3 of the grass carp reovirus (Genus Aquareovirus, family Reoviridae). Biochem Biophys Res Commun 274:762–766CrossRefPubMedGoogle Scholar
  8. Fang Q, Shah S, Liang Y, Zhou ZH (2005) 3D reconstruction and capsid protein characterization of grass carp reovirus. Sci China C Life Sci 48:593–600CrossRefPubMedGoogle Scholar
  9. Ivanovic T, Agosto MA, Zhang L, Chandran K, Harrison SC, Nibert ML (2008) Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. EMBO J 27:1289–1298CrossRefPubMedPubMedCentralGoogle Scholar
  10. Li X, Fang Q (2013) High-resolution 3D structures reveal the biological functions of reoviruses. Virol Sin 28:318–325CrossRefPubMedGoogle Scholar
  11. Rangel AA, Rockemann DD, Hetrick FM, Samal SK (1999) Identification of grass carp haemorrhage virus as a new genogroup of aquareovirus. J Gen Virol 80(Pt 9):2399–2402CrossRefPubMedGoogle Scholar
  12. Shaw AL, Samal SK, Subramanian K, Prasad BV (1996) The structure of aquareovirus shows how the different geometries of the two layers of the capsid are reconciled to provide symmetrical interactions and stabilization. Structure 4:957–967CrossRefPubMedGoogle Scholar
  13. Snyder AJ, Danthi P (2017) The reovirus mu1 340-343 loop controls entry related conformational changes. J Virol. pii: JVI.00898-17Google Scholar
  14. Tuthill TJ, Bubeck D, Rowlands DJ, Hogle JM (2006) Characterization of early steps in the poliovirus infection process: receptor-decorated liposomes induce conversion of the virus to membrane-anchored entry-intermediate particles. J Virol 80:172–180CrossRefPubMedPubMedCentralGoogle Scholar
  15. Yan S, Zhang J, Guo H, Yan L, Chen Q, Zhang F, Fang Q (2015) VP5 autocleavage is required for efficient infection by in vitro-recoated aquareovirus particles. J Gen Virol 96:1795–1800CrossRefPubMedGoogle Scholar
  16. Zhang X, Jin L, Fang Q, Hui WH, Zhou ZH (2010) 3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry. Cell 141:472–482CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Wuhan Institute of Virology, CAS and Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.State Key Laboratory of VirologyWuhan Institute of Virology, Chinese Academy of SciencesWuhanChina

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