Virologica Sinica

, Volume 32, Issue 3, pp 226–234 | Cite as

Detection of diverse viruses in alimentary specimens of bats in Macau

  • Jie Liang
  • Xing-Lou Yang
  • Bei Li
  • Qi Liu
  • Qin Zhang
  • Hui Liu
  • Hon-Pio Kan
  • Kai-Chin Wong
  • Si-Nga Chek
  • Xiangyang He
  • Xingwen Peng
  • Zheng-Li Shi
  • Yi Wu
  • Libiao Zhang
Research Article


Bats carry a variety of viruses, and some of them cause public health problems. Macau, which is famous for its gambling industry, has a complex population structure. The globalization in such an international metropolis has enhanced the chance of disease transmission. Therefore, surveillance of zoonotic viruses is necessary for the early warning of potential emerging infectious diseases. Here, we report the first surveillance of bat viruses in Macau. In this study, we collected 1004 samples involving 10 bat species from 7 sites from April 2015 to May 2016, and examined the presence of viruses using nucleic acid-based methods. Coronaviruses, adenoviruses and paramyxoviruses were detected in these samples, with a high prevalence of coronaviruses. While, none was positive for hepatitis A virus, hepatitis E virus or hantavirus. Co-infections are not common in those bat species, but coronavirus HKU6 and adenovirus can be found commonly occurred in Myotis ricketti.


viral detection bat virus coronavirus adenovirus paramyxovirus 


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We thank Feili Guo, Qiujian Li, Shaofang Hu and Bingrong Liu for helping with the sample collection. We thank Xiangling Liu for helping with viral isolation. We thank Ben Hu for article revision. This work was financed by the Environment Construction & Capacity Building of GDAS’ Research Platform (2016GDASPT- 0215), the Science & Technology Planning Project of Guangdong (2013B050800024 and 2015A020209093) and Science & Technology Planning Project of Guangzhou (201707010128).


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Copyright information

© Wuhan Institute of Virology, CAS and Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.College of Life ScienceGuangzhou UniversityGuangzhouChina
  2. 2.Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and UtilizationGuangdong Institute of Applied Biological ResourcesGuangzhouChina
  3. 3.CAS Key Laboratory of Special Pathogens, Center for Emerging Infectious Diseases, Wuhan Institute of VirologyChinese Academy of SciencesWuhanChina
  4. 4.Macau Civic and Municipal Affairs BureauMacao SARChina

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