Virologica Sinica

, Volume 32, Issue 1, pp 32–43 | Cite as

Hantavirus infection: a global zoonotic challenge

  • Hong Jiang
  • Xuyang Zheng
  • Limei Wang
  • Hong Du
  • Pingzhong WangEmail author
  • Xuefan BaiEmail author


Hantaviruses are comprised of tri-segmented negative sense single-stranded RNA, and are members of the Bunyaviridae family. Hantaviruses are distributed worldwide and are important zoonotic pathogens that can have severe adverse effects in humans. They are naturally maintained in specific reservoir hosts without inducing symptomatic infection. In humans, however, hantaviruses often cause two acute febrile diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). In this paper, we review the epidemiology and epizootiology of hantavirus infections worldwide.


hantavirus Bunyaviridae zoonosis hemorrhagic fever with renal syndrome hantavirus cardiopulmonary syndrome 


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The authors would like to thank Mr. An Yang from the Department of Foreign Languages, Fourth Military Medical University, China, for improving the English manuscript. This work was supported by the National Natural Science Foundation of China (No. 81373118) and the National Basic Research Programme of China (973 Programme No. 2012CB518905).


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Copyright information

© Wuhan Institute of Virology, CAS and Springer Science+Business Media Singapore 2017

Authors and Affiliations

  1. 1.Center for Infectious Diseases, Tangdu HospitalFourth Military Medical UniversityXi’anChina
  2. 2.Department of Microbiology, School of Basic MedicineFourth Military Medical UniversityXi’anChina

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