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RETRACTED ARTICLE: Phylogenetic analysis of the non-structural (NS) gene of influenza a viruses isolated in Kazakhstan in 2002–2009

Virologica Sinica volume 26, pages 376–385 (2011)Cite this article

This article was retracted on 28 November 2013

Abstract

Although the important role of the non-structural (NS1 and NEP) gene of influenza A in virulence of the virus is well established, our knowledge about the extent of variation in the NS gene pool of influenza A viruses in their natural reservoirs in Kazakhstan is incomplete. 17 influenza A viruses of different subtypes were studied in this paper. Seven types of haemagglutinin and five different neuraminidase subtypes in eight combinations were found among the isolated viruses. A comparison of nucleotide sequences of isolated viruses revealed a substantial number of silent mutations, which results in high degree of homology in amino acid sequences. By phylogenetic analysis it was shown that two distinct gene pools, corresponding to both NS allele A with 5 Clades and B, were present at the same time in Kazakhstan. The degree of variation within the alleles was very low. In our study allele A viruses had a maximum of 5% amino acid divergence in Clade while allele B viruses had only 4% amino acid divergence.

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Authors and Affiliations

  1. Institute of Microbiology & Virology, 103, Bogenbay batyr Str, Almaty, 050010, Kazakhstan

    Andrey Bogoyavlenskiy, Vladimir Berezin, Ilya Korotetskiy, Irina Zaitseva, Aydyn Kydyrmanov, Kobey Karamedin, Nailya Ishmukhametova, Saule Asanova, Marat Sayatov & Kainar Zhumatov

  2. Ivanovsky Institute of Virology, 16, Gamaleya str, Moscow, 123098, Russia

    Alexey Prilipov

Authors
  1. Andrey Bogoyavlenskiy
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  2. Vladimir Berezin
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  4. Ilya Korotetskiy
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Corresponding author

Correspondence to Andrey Bogoyavlenskiy.

Additional information

Foundation items: USDA-ISTC(The International Science and Technology Center) partner project #K-747p; Institute of Microbiology and Virology project #0103KZO0126 and #0106KZ00581.

An erratum to this article is available at http://dx.doi.org/10.1007/s12250-013-3374-x.

This article has been retracted at the request of the Editor-in-Chief, as it contains large portions of text that have been duplicated from “Phylogenetic analysis of the non-structural (NS) gene of influenza A viruses isolated from mallards in Northern Europe in 2005” published in Virology Journal (2008) 5:147, without sufficient attribution being given to the article. Despite the data / conclusion being original in the paper, this is violating the journal policy.

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Bogoyavlenskiy, A., Berezin, V., Prilipov, A. et al. RETRACTED ARTICLE: Phylogenetic analysis of the non-structural (NS) gene of influenza a viruses isolated in Kazakhstan in 2002–2009. Virol. Sin. 26, 376–385 (2011). https://doi.org/10.1007/s12250-011-3208-7

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  • DOI: https://doi.org/10.1007/s12250-011-3208-7

Key words

  • Influenza
  • Nonstructural gene
  • Phylogenetic analysis