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Laboratory detection and diagnosis of filoviruses

Virologica Sinica volume 26, pages 73–80 (2011)Cite this article

Abstract

Ebola virus (EBOV) and Marburg virus (MARV), belonging to the Filoviridae family, emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates. As high as 50–90% mortality, filoviruses can cause significant threats to public health. However, so far no specific and efficient vaccine has been available, nor have other treatment methods proved to be effective. It is of great importance to detect these pathogens specific, rapidly and sensitively in order to control future filovirus outbreaks. Here, recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized.

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Authors and Affiliations

  1. State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China

    Yun-peng Wang, Xian-en Zhang & Hong-ping Wei

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  1. Yun-peng Wang
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  2. Xian-en Zhang
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  3. Hong-ping Wei
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Correspondence to Hong-ping Wei.

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Wang, Yp., Zhang, Xe. & Wei, Hp. Laboratory detection and diagnosis of filoviruses. Virol. Sin. 26, 73–80 (2011). https://doi.org/10.1007/s12250-011-3186-9

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  • DOI: https://doi.org/10.1007/s12250-011-3186-9

Key words

  • Filovirus
  • Ebola virus (EBOV)
  • Marburg virus (MARV)
  • Enzyme-linked immunosorbent assay (ELISA)
  • Polymerase chain reaction (PCR)