A Framework for Assessing Disruptions in a Clinical Supply Chain Using Bayesian Belief Networks
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Clinical trial study failures cause significant disruptions to supply chain operations, which lead to operational inefficiencies and financial losses.
In this paper, a framework to construct a Bayesian belief network (BBN) by leveraging subject matter expertise and probabilistic elicitation methods to quantify the probability of a disruption to a clinical supply chain is presented.
The effect of varying input factors on a disruption probability is studied, and new metrics are developed to evaluate the significance of a disruption.
This framework allows practitioners to assess the probability of disruptions to their network, thus enabling targeted strategies to be developed and implemented.
KeywordsBayesian belief networks Clinical trials Disruption Risk analysis Supply chain management Probabilistic elicitation
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflict of interest.
For this type of study, formal consent is not required.
Informed consent was obtained from all individual participants included in the study.
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