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Preparation and Properties of Water-Resistant Antibacterial Curcumin/Silver Composite Nanofiber

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Abstract

The water-resistant antibacterial PVA nanofibers containing curcumin (Cur) and silver nanoparticles (AgNPs) were prepared by electrospinning, and the AgNps were prepared by in situ reduction in the spinning solution. The prepared PVA nanofibers were measured by scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), and Fourier transform infrared spectrophotometer (FT-IR). The breathable, hygroscopic, antibacterial, anti-inflammatory, and antioxidants functions of the prepared nanofibers were evaluated. The results indicated that the prepared nanofiber membrane has high swelling rate, moisture permeability, good mechanical properties, good biocompatibility, anti-inflammatory, antioxidant, and bacteriostatic activities with no cytotoxicity. Curcumin and AgNPs in the prepared nanofiber have effect on antibacterial activity and wound healing. The functionalized silver nanoparticles developed have effective activities against both Gram-negative bacteria and Gram-positive bacteria. In short, Cur/AgNPs composite nanofibers can be used as a potential medical dressing with antibacterial, anti-inflammatory, and antioxidant properties.

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Acknowledgements

This work is supported by the National Natural Science Foundation of China (No. 21706093)

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National Natural Science Foundation of China, 21706093, Rong Li.

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  1. Key Laboratory of Eco-Textiles of Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, 214122, Jiangsu, China

    Meiping Chen, Chao Ma, Change Zhou, Zhiguang Li & Rong Li

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Chen, M., Ma, C., Zhou, C. et al. Preparation and Properties of Water-Resistant Antibacterial Curcumin/Silver Composite Nanofiber. Fibers Polym 24, 3821–3832 (2023). https://doi.org/10.1007/s12221-023-00346-x

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