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Magnetic-Field-Assisted Emulsion Electrospinning System: Designing, Assembly, and Testing for the Production of PCL/Gelatin Core–Shell Nanofibers

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Abstract

There are different methods for producing core–shell nanofibers, one of which is the emulsion electrospinning method. The stability of the emulsion during electrospinning is one of the most critical factors in the quality of the fibers. In this study, a magnetic-field-assisted emulsion electrospinning system was designed, built, and tested to keep the emulsion stable without additives or sonication. Polycaprolactone (PCL) 10 wt. % in dichloromethane (DCM) for the shell and gelatin 2.5 wt. % in water for the core was used. Scanning electron microscope (SEM) image of samples with different weight ratios of components both with and without using the magnetic-field-assisted emulsion electrospinning system at different rotational speeds was investigated. Transition electron microscope (TEM) images of the sample with a ratio of 1/10 (gel/PCL) at different rotational speeds were studied. The fibers were finally analyzed by Fourier transform infrared (FTIR) and tensile strength machine. According to the results, there was no change in the bonds in the materials after electrospinning. The designed system improved the fiber texture and reduced its structural problems significantly. By increasing the rotation speed of the magnet from 700 to 900 rpm, an improvement in fiber morphology and uniformity in diameter was observed. The composition of gelatin/PCL with a ratio of 1/10 was selected as the optimal condition. The spun nanofibers in these conditions had a uniform structure without the bead, and the presence of both polymers uniformly in the fibers was shown. Finally, the magnetic-field-assisted emulsion electrospinning system successfully held the emulsion stable during electrospinning without additives.

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References

  1. N. Bhardwaj, S.C. Kundu, Biotechnol. Adv. 28, 325 (2010)

    Article  CAS  PubMed  Google Scholar 

  2. N. Jirofti, D. Mohebbi-Kalhori, A. Samimi, A. Hadjizadeh, G.H. Kazemzadeh, Biomed. Mater. 13, 55014 (2018)

    Article  Google Scholar 

  3. H. Savoji, A. Hadjizadeh, M. Maire, A. Ajji, M.R. Wertheimer, S. Lerouge, Macromol. Biosci. 14, 1084 (2014)

    Article  CAS  PubMed  Google Scholar 

  4. J. Yang, Sci. Prepr. (2022). https://doi.org/10.14293/S2199-1006.1.SOR-.PPOFGWR.v1

    Article  Google Scholar 

  5. M.F. Elahi, W. Lu, G. Guoping, F. Khan, J. Bioeng. Biomed. Sci 3, 1 (2013)

    Article  Google Scholar 

  6. W. Xia, G. Peng, Y. Hu, G. Dou, Polym. Eng. Sci. 62, 247 (2022)

    Article  CAS  Google Scholar 

  7. A. Hasan, A. Memic, N. Annabi, M. Hossain, A. Paul, M.R. Dokmeci, F. Dehghani, A. Khademhosseini, Acta Biomater. 10, 11 (2014)

    Article  CAS  PubMed  Google Scholar 

  8. T. Jiang, E.J. Carbone, K.W.-H. Lo, C.T. Laurencin, Prog. Polym. Sci. 46, 1 (2015)

    Article  Google Scholar 

  9. W. Chen, D. Li, E.-S. Ahmed, M. El-Newehy, H.A. Ei-Hamshary, S.S. Al-Deyab, C. He, X. Mo, Colloids Surf. B Biointerfaces 126, 561 (2015)

    Article  CAS  PubMed  Google Scholar 

  10. S. Agarwal, J.H. Wendorff, A. Greiner, Polymer (Guildf) 49, 5603 (2008)

    Article  CAS  Google Scholar 

  11. R. Ramalingam, C. Dhand, C.M. Leung, H. Ezhilarasu, P. Prasannan, S.T. Ong, S. Subramanian, M. Kamruddin, R. Lakshminarayanan, S. Ramakrishna et al., Nanomaterials 9, 462 (2019)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. M. Badmus, J. Liu, N. Wang, N. Radacsi, Y. Zhao, Nano Mater. Sci. 3, 213 (2021)

    Article  CAS  Google Scholar 

  13. J. Avossa, G. Herwig, C. Toncelli, F. Itel, R. M. Rossi, Green Chem. 24, 2347 (2022)

    Article  CAS  Google Scholar 

  14. N. Nikmaram, S. Roohinejad, S. Hashemi, M. Koubaa, F.J. Barba, A. Abbaspourrad, R. Greiner, RSC Adv. 7, 28951 (2017)

    Article  CAS  Google Scholar 

  15. K. Zhou, M. Wang, Y. Zhou, M. Sun, Y. Xie, D.-G. Yu, Adv. Compos. Hybrid Mater. 5, 907 (2022)

    Article  Google Scholar 

  16. A. Barhoum, K. Pal, H. Rahier, H. Uludag, I.S. Kim, M. Bechelany, Appl. Mater. Today 17, 1 (2019)

    Article  Google Scholar 

  17. X. Qin, Coaxial electrospinning of nanofibers, in Electrospun nanofibers, Elsevier (2017), pp. 41–71.

  18. F. Li, Y. Zhao, Y. Song, Nanofibers 2, 418 (2010)

    Google Scholar 

  19. X. Xu, X. Chen, X. Wang, X. Jing et al., Eur. J. Pharm. Biopharm. 70, 165 (2008)

    Article  CAS  PubMed  Google Scholar 

  20. X. Xu, L. Yang, X. Xu, X. Wang, X. Chen, Q. Liang, J. Zeng, X. Jing, J. Control. Release 108, 33 (2005)

    Article  CAS  PubMed  Google Scholar 

  21. P.J. Garc’ia-Moreno, K. Stephansen, J. van der Kruijs, A. Guadix, E.M. Guadix, I.S. Chronakis, C. Jacobsen, J. Food Eng. 183, 39 (2016)

    Article  Google Scholar 

  22. M.F. Abdullah, T. Nuge, A. Andriyana, B.C. Ang, F. Muhamad, Polymers (Basel) 11, 2008 (2019)

    Article  CAS  PubMed  Google Scholar 

  23. F. Kashani-Asadi-Jafari, A. Hadjizadeh, Pharm. Nanotechnol. 56, 10 (2022)

    Google Scholar 

  24. F. Kashani-Asadi-Jafari, A. Aftab, S. Ghaemmaghami, Int. J. Pharm. 627, 122203 (2022)

    Article  CAS  PubMed  Google Scholar 

  25. J. Hu, M.P. Prabhakaran, X. Ding, S. Ramakrishna, J. Biomater. Sci. Polym. Ed. 26, 57 (2015)

    Article  CAS  PubMed  Google Scholar 

  26. A. Hadjizadeh, A. Ajji, M.N. Bureau, J. Mech. Behav. Biomed. Mater. 4, 340 (2011)

    Article  PubMed  Google Scholar 

  27. R.K. Mishra, A.B.A. Majeed, A.K. Banthia, Int. J. Plast. Technol. 15, 82 (2011)

    Article  CAS  Google Scholar 

  28. Y. Wu, X. Qiu, S. Cao, J. Chen, X. Shi, Y. Du, H. Deng, J. Colloid Interface Sci. 539, 533 (2019)

    Article  CAS  PubMed  Google Scholar 

  29. A.L. Yarin, Polym. Adv. Technol. 22, 310 (2011)

    Article  CAS  Google Scholar 

  30. G.H. Kim, H. Nam, W. Choi, T. An, G. Lim, Adv. Mater. Interfaces 5, 1701204 (2018)

    Article  Google Scholar 

  31. C.J. Angammana, S.H. Jayaram, IEEE Trans. Ind. Appl. 47, 1028 (2011)

    Article  Google Scholar 

  32. J.-H. He, Y.-Q. Wan, Int. J. Nonlinear Sci. Numer. Simul. 5, 243 (2004)

    CAS  Google Scholar 

  33. Y. Dai, J. Niu, J. Liu, L. Yin, J. Xu, Bioresour. Technol. 101, 8942 (2010)

    Article  CAS  PubMed  Google Scholar 

  34. K. Wang, X. Chen, Y. Pan, Y. Cui, X. Zhou, D. Kong, Q. Zhao, Biomed Res. Int. 2015, 865076 (2015)

    PubMed  PubMed Central  Google Scholar 

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Acknowledgements

We thank Mr. Arya Aftab for his kind help in writing the article in terms of language editing. We also thank the Amirkabir University of Technology for providing laboratory equipment and funding for this study.

Funding

This study was funded by Amirkabir University of Technology (Grant No. GN2020).

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Authors and Affiliations

  1. Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, 159163-4311, Iran

    Fatemeh Kashani-Asadi-Jafari, Ahmadreza Parhizgar & Afra Hadjizadeh

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  1. Fatemeh Kashani-Asadi-Jafari
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  2. Ahmadreza Parhizgar
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  3. Afra Hadjizadeh
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Correspondence to Afra Hadjizadeh.

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Kashani-Asadi-Jafari, F., Parhizgar, A. & Hadjizadeh, A. Magnetic-Field-Assisted Emulsion Electrospinning System: Designing, Assembly, and Testing for the Production of PCL/Gelatin Core–Shell Nanofibers. Fibers Polym 24, 515–523 (2023). https://doi.org/10.1007/s12221-023-00111-0

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