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Translocation of charged particles through a thin micropore under pressure-driven flow

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Abstract

We report the effects of a particle surface charge during translocation through a thin micropore based on the simulation and experiments. The translocation of carboxylated and nonfunctionalized polystyrene beads through a fabricated micropore was measured. To compare the translocation behaviors of a particle with/without surface charge under the same driving force, we used a pressure-driven method low bias voltage. We then analyzed the signals with two factors: the translocation time and blocking current. Based on the analysis, we found that, at a low flow rate, the translocation time was largely dependent on the surface charge of the particles. More importantly, we found an unusual phenomenon that the flow rate can affect the blocking current, and the level of effect was significantly determined by the particle’s surface charge. To understand this phenomenon, we suggest a plausible mechanism considering the effect of the convective flow on the counterion flux and FEM results.

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Acknowledgments

This work was supported by the Basic Science Research Program (2021R1A2B5B03001811), STEAM Program (2022 M3C1A3081178) and ERC program (2016M3D1A1952991) through the National Research Foundation, funded by the Ministry of Science and ICT, Korea.

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Author notes

  1. These authors equally contributed to this work as first author.

Authors and Affiliations

  1. School of Mechanical and Engineering, Korea University, Seoul, 02841, Korea

    Junsang Moon, Chang Woo Song & Chang-Soo Han

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  1. Junsang Moon
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  2. Chang Woo Song
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  3. Chang-Soo Han
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Corresponding author

Correspondence to Chang-Soo Han.

Additional information

Junsang Moon received his M.S., and B.S. degrees in Mechanical Engineering from Korea University, in 2021, and in 2019, respectively. His research interests were focused on microparticle detection using micropore sensors.

Chang-Woo Song is an integrated Ph.D. program candidate in the School of Mechanical Engineering, Korea University, Seoul, Korea. He received his B.S. degree in Mechanical Engineering from Korea University, in 2018. His research interests are focused on microparticle detection using micropore sensor.

Chang-Soo Han is a Professor in Korea University, Seoul, Korea. He got B.S. and M.S. degrees in Seoul National University and worked for Samsung Electronics Co. for 6 years. He received his Ph.D. degree in Mechanical Engineering from KAIST in 2000. And he worked in KIMM for 11 years and moved to Korea University in 2011. His research interests are biomimetic materials, sensors and systems in the nanoscale.

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Moon, J., Song, C.W. & Han, CS. Translocation of charged particles through a thin micropore under pressure-driven flow. J Mech Sci Technol 36, 5181–5189 (2022). https://doi.org/10.1007/s12206-022-0930-z

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  • DOI: https://doi.org/10.1007/s12206-022-0930-z

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