Abstract
Silver nanoparticles (AgNPs) have garnered significant interest owing to their unique properties and therefore, AgNPs have widespread application. However, there have been recent reports about the risks posed by AgNPs to human health and a highly sensitive tool for detecting AgNPs in aquatic environments is required to prevent their harmful effects on humans. In this article, we propose highly sensitive detection of AgNPs using a micro-resonator and the DNA assisted conjugation method. The detection method is based on the resonance frequency shift of the resonator upon adsorption of conjugated AgNPs. We have used the DNA assisted AgNPs conjugation method to amplify the mass of the detection target. By using this micro-resonator in combination with the conjugation method, we were able to achieve highly sensitive and selective detection of AgNPs, with detection limits of approximately 10 ng/mL in distilled water, which is at least 10 times more sensitive than that described in previous reports. Further, we also performed detection in real drinking water samples.
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Acknowledgments
This work was supported by the Academic Research fund of Hoseo University in 2017 under Grant Number (20170090).
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Recommended by Editor Chang-Soo Han
Kyoungwoo Park is a Professor in the School of Mechanical Engineering at Hoseo University. He received B.S., M.S. and Ph.D. in mechanical engineering at Hanyang University. His principle research interests include microfluids, computational fluid dynamics (CFD) and nanomaterials.
Kuewhan Jang is a Professor in the School of Mechanical Engineering at Hoseo University. He received B.S. and Ph.D. in mechanical engineering from Korea University. His research interests include mechanical resonator, nanomaterial and nucleic acids sensors.
Sungsoo Na is a Professor in the Department of Engineering Science and Mechanics at Korea University. He received B.S. and M.S. in engineering science and mechanics at Korea University and received Ph.D. in engineering science and mechanics at Virginia Polytechnic Institue & State University. His principle research interests include nanomaterial and bio sensors, and multi-scale protein dynamics.
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Jang, K., Park, C., Park, W. et al. A method for highly sensitive detection of silver nanoparticles using a micro-resonator and DNA assisted conjugation. J Mech Sci Technol 34, 1675–1681 (2020). https://doi.org/10.1007/s12206-020-0330-1
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DOI: https://doi.org/10.1007/s12206-020-0330-1