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A study of fluid dynamics parameters for prediction of obstructive sleep apnea

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Abstract

Obstructive sleep apnea (OSA) is a syndrome characterized by the repetitive episodic collapse of the upper airway. The purpose of this study is to investigate the fluid dynamic parameters for the prediction of obstructive sleep apnea in the upper airway before and after setback surgery. Here, we analyzed the flow phenomena of inspiration and expiration in obstructive sleep apnea patients. The modeling of the upper airway was performed with facial 3 dimensional facial computed tomography images (3D facial CT). We used timedependent value for boundary conditions. The changes of pressure were studied with 3D facial CT taken both before and after the setback surgery. Further, it was found that the correlation between PSG data and non-dimensional pressure drop can be used to predict the severity of OSA. In all 6 patients except for patient 1, the average values of the non-dimensional pressure drops and PSG clinical data are inversely related. For each patient, the lower the pressure drop is, the higher the PSG values will be.

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Authors and Affiliations

  1. Dept. of Mechanical Engineering, Soongsil University, Seoul, 06978, Korea

    Hyoung-Ho Kim, Md Rakibuzzaman & Sang-Ho Suh

  2. Department of Otorhinolaryngology, College of Medicine, Seoul National University, Seoul, Korea

    Hyun-Jik Kim

  3. Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea

    Jin-Young Choi

  4. Department of Oral and Maxillofacial Surgery, Chung-Ang University Hospital, Seoul, Korea

    Ui-Lyong Lee

Authors
  1. Hyoung-Ho Kim
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  2. Md Rakibuzzaman
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  3. Sang-Ho Suh
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  4. Hyun-Jik Kim
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  5. Jin-Young Choi
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  6. Ui-Lyong Lee
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Corresponding author

Correspondence to Ui-Lyong Lee.

Additional information

This paper was presented at the ICCHM2T2017, Sejong Hotel, Seoul, Korea, May 28–June 1, 2017. Recommended by Guest Editor Heuy Dong Kim.

Hyoung-Ho Kim is a Researcher at Soongsil University, Seoul, Korea. He is currently a Ph.D. Student at Soongsil University under the supervision of Prof. Dr.–Ing. Sang-Ho Suh. His research interests include biofluids, and turbo machinery fields.

Md Rakibuzzaman is a Researcher at Soongsil University, Seoul, Korea. He is currently a Ph.D. student at Soongsil University under the supervision of Prof. Dr.–Ing. Sang-Ho Suh. His research interests include cavitation phenomena in turbo machinery and biomedical engineering.

Sang-Ho Suh is a Professor of Dept. of Mechanical Engineering at Soongsil University, Seoul, Korea. He received his Ph.D. degree from Stuttgart University in 1989. He has been teaching at Soongsil University since 1990. His research contributions were in the field of fluid machinery and Biofluid engineering. He is currently working on biomedical engineering research includes biofluid circulations (Blood, urine and air flows in arteries, ureter, upper airway), development of biomedical devices, and industrial application researches of performance evaluation of pumps and hydraulic turbines, development of automatic waste collecting system, Pneumatic capsule pipeline (PCP).

Hyun Jik Kim is an Associate Professor of Otorhinolaryngology at Seoul Nantional University, Seoul, South Korea. He received his M.D. and Ph.D. degrees from Seoul National University. His research contributions were in the field of relationship between reactive oxygen species and viral immunology in airway epithelium and development of therapeutic material against viral respiratory infection for respiratory mucosal innate immunity.

Jin-Young Choi is a Professor of Oral and Maxillofacial Surgery at Seoul Nantional University, Seoul, Korea. He received his D.D.S. from Seoul National University, M.D. and Ph.D. degrees from Georg-August University, in Goettingen, Germany. His research contributions were in the field of Oral and Maxillofacial surgery.

Ui-Lyong Lee is a Clinical Assist Professor of Oral & Maxillofacial Surgery at Chung-Ang University Hospital, Seoul, Korea. He received his M.S.D. degree from Seoul National University in 2006. His research contributions were in the field of Orthognathic surgery and patient specific 3D printing implant. He is currently working on biomedical engineering research includes periodontal tissue bio-printing and microfluidics.

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Kim, HH., Rakibuzzaman, M., Suh, SH. et al. A study of fluid dynamics parameters for prediction of obstructive sleep apnea. J Mech Sci Technol 32, 1079–1085 (2018). https://doi.org/10.1007/s12206-018-0210-0

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  • DOI: https://doi.org/10.1007/s12206-018-0210-0

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