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Application of 3D Digital Reconstruction and Printing to the Diagnosis and Treatment of Iliac Vein Compression

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Abstract

The objective of this research was to explore the feasibility and clinical application of a new diagnostic imaging method for the diagnosis and treatment of iliac vein compression (IVC) based on three-dimensional (3D) digital reconstruction and printing. This study included patients with chronic venous disease (CVD) who were admitted to the Department of Vascular Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, from January to March, 2019, and underwent computed tomography venography (CTV) to detect IVC. CTV findings were used to reconstruct 3D-printed models of blood vessels. A total of 17 patients (5 men and 12 women) with IVC, who were primarily diagnosed with CTV, were included in this study. In addition, 24 significant venous compression sites were found in 17 patients, of which 7 patients had only one compression site (41.2%), nine patients had two compression sites (52.9%), and one patient had three compression sites (5.9%). 3D digital reconstruction and printing is a convenient, noninvasive, and accurate diagnostic imaging method that provides a clear and accurate evaluation of veins and arteries, as well as the anatomical positional relationship for the diagnosis and treatment of IVC.

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References

  1. MAY R, THURNER J. The cause of the predominantly sinistral occurrence of thrombosis of the pelvic veins [J]. Angiology, 1957, 8(5): 419–427.

    Article  Google Scholar 

  2. RADAIDEH Q, PATEL N M, SHAMMAS N W. Iliac vein compression: Epidemiology, diagnosis and treatment [J]. Vascular Health and Risk Management, 2019, 15: 115–122.

    Article  Google Scholar 

  3. HEIJMEN R H, BOLLEN T L, DUYNDAM D A, et al. Endovascular venous stenting in May-Thurner syndrome [J]. The Journal of Cardiovascular Surgery, 2001, 42(1): 83–87.

    Google Scholar 

  4. YIN M Y, TIAN S, HUANG X T, et al. Role and mechanism of tissue plasminogen activator in venous wall fibrosis remodeling after deep venous thrombosis via the glycogen synthase kinase-3 beta signaling pathway [J]. Journal of Surgical Research, 2013, 184(2): 1182–1195.

    Article  Google Scholar 

  5. HARBIN M M, LUTSEY P L. May-Thurner syndrome: History of understanding and need for defining population prevalence [J]. Journal of Thrombosis and Haemostasis, 2020, 18(3): 534–542.

    Article  Google Scholar 

  6. BURKE R M, RAYAN S S, KASIRAJAN K, et al. Unusual case of right-sided May-Thurner syndrome and review of its management [J]. Vascular, 2006, 14(1): 47–50.

    Article  Google Scholar 

  7. ABBOUD G, MIDULLA M, LIONS C, et al. “Rightsided” may-thurner syndrome [J]. CardioVascular and Interventional Radiology, 2010, 33(5): 1056–1059.

    Article  Google Scholar 

  8. KIBBE M R, UJIKI M, GOODWIN A L, et al. Iliac vein compression in an asymptomatic patient population [J]. Journal of Vascular Surgery, 2004, 39(5): 937–943.

    Article  Google Scholar 

  9. KNUTTINEN M G, NAIDU S, OKLU R, et al. May-Thurner: Diagnosis and endovascular management [J]. Cardiovascular Diagnosis and Therapy, 2017, 7(Sup. 3): S159–S164.

    Article  Google Scholar 

  10. YIN M Y, HUANG X T, CUI C Y, et al. The effect of stent placement for May-Thurner syndrome combined with symptomatic superficial venous reflux disease [J]. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2015, 3(2): 168–172.

    Google Scholar 

  11. EKLÖF B, RUTHERFORD R B, BERGAN J J, et al. Revision of the CEAP classification for chronic venous disorders: Consensus statement [J]. Journal of Vascular Surgery, 2004, 40(6): 1248–1252.

    Article  Google Scholar 

  12. BRINEGAR K N, SHETH R A, KHADEMHOSSEINI A, et al. Iliac vein compression syndrome: Clinical, imaging and pathologic findings [J]. World Journal of Radiology, 2015, 7(11): 375–381.

    Article  Google Scholar 

  13. BIRN J, VEDANTHAM S. May-Thurner syndrome and other obstructive iliac vein lesions: Meaning, myth, and mystery [J]. Vascular Medicine, 2015, 20(1): 74–83.

    Article  Google Scholar 

  14. ZUCKER E J, GANGULI S, GHOSHHAJRA B B, et al. Imaging of venous compression syndromes [J]. Cardiovascular Diagnosis and Therapy, 2016, 6(6): 519–532.

    Article  Google Scholar 

  15. SHAMMAS N W, RACHWAN R J, DAHER G, et al. Double inferior vena cava and its implications during endovascular and surgical interventions: A word of caution [J]. The Journal of Invasive Cardiology, 2017, 29(2): 51–53.

    Google Scholar 

  16. WHITE J M, COMEROTA A J. Venous compression syndromes [J]. Vascular and Endovascular Surgery, 2017, 51(3): 155–168.

    Article  Google Scholar 

  17. LABROPOULOS N, BORGE M, PIERCE K, et al. Criteria for defining significant central vein stenosis with duplex ultrasound [J]. Journal of Vascular Surgery, 2007, 46(1): 101–107.

    Article  Google Scholar 

  18. FRETZ V, BINKERT C A. Compression of the inferior vena cava by the right iliac artery: A rare variant of may-thurner syndrome [J]. CardioVascular and Interventional Radiology, 2010, 33(5): 1060–1063.

    Article  Google Scholar 

  19. SHI W Y, GU J P, LIU C J, et al. Dual compression is not an uncommon type of iliac vein compression syndrome [J]. The International Journal of Cardiovascular Imaging, 2017, 33(9): 1277–1285.

    Article  Google Scholar 

  20. QU Y, AI S T, YANG F, et al. Application of CT/MRI image registration and fusion combined with 3D printing technique in pre-surgical planning of refractory pelvic tumors [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2017, 37(9): 1238–1244 (in Chinese).

    Google Scholar 

  21. QU Y, AI S T, WU W, et al. Preliminary application of 3D printed customized guide in bone tumor biopsy [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2018, 38(9): 1053–1058 (in Chinese).

    Google Scholar 

  22. LIU G, ZHAO Z, CUI C, et al. Endovascular management of extensive lower extremity acute deep vein thrombosis with AngioJet rheolytic thrombectomy plus catheter-directed thrombolysis from contralateral femoral access [J]. Phlebology, 2019, 34(4): 257–265.

    Article  Google Scholar 

  23. LU X W, LI W M, HUANG Y, et al. The clinical values of subintimal angioplasty for treatment lower extremity arterial occlusions [J]. National Medical Journal of China, 2007, 87(43): 3047–3050.

    Google Scholar 

  24. STRANDNESS D E, SUMNER D S. Hemodynamics for surgeons[M]. New York: Grune and Stratton; 1975: 108–117.

    Google Scholar 

  25. SATOKAWA H, HOSHINO S, IWAYA F, et al. Intravascular imaging methods for venous disorders [J]. International Journal of Angiology, 2000, 9(2): 117–121.

    Article  Google Scholar 

  26. RAJU S, NEGLEN P. High prevalence of nonthrombotic iliac vein lesions in chronic venous disease: A permissive role in pathogenicity [J]. Journal of Vascular Surgery, 2006, 44(1): 136–144.

    Article  Google Scholar 

  27. LEVITIN A. Intravascular ultrasound [J]. Techniques in Vascular and Interventional Radiology, 2001, 4(1): 66–74.

    Article  Google Scholar 

  28. CAGGIATI A. The left common iliac artery also compresses the left common iliac vein [J]. Journal of Vascular Surgery, 2011, 54(6): 56S–61S.

    Article  Google Scholar 

  29. AYARAJ A, RAJU S. Three-dimensional computed tomography venogram enables accurate diagnosis and treatment of patients presenting with symptomatic chronic iliofemoral venous obstruction [J]. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2021, 9(1): 73–80.e1.

    Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Vascular Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China

    Chenghao Yang  (杨成昊), Xinwu Lu  (陆信武), Kaichuang Ye  (叶开创), Zhen Zhao  (赵振), Xuhui Wang  (王旭辉), Penghui Wang  (王鹏辉) & Minyi Yin  (殷敏毅)

  2. Department of Orthopedics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China

    Wenbo Jiang  (姜闻博)

  3. Image Medraw Technology (Shanghai) Co., Ltd., Shanghai, 200240, China

    Yebao Fei  (费业宝) & Wei Wang  (王伟)

Authors
  1. Chenghao Yang  (杨成昊)
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  2. Xinwu Lu  (陆信武)
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  3. Wenbo Jiang  (姜闻博)
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  4. Kaichuang Ye  (叶开创)
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  5. Zhen Zhao  (赵振)
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  6. Xuhui Wang  (王旭辉)
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  7. Penghui Wang  (王鹏辉)
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  8. Yebao Fei  (费业宝)
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  9. Wei Wang  (王伟)
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  10. Minyi Yin  (殷敏毅)
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Corresponding author

Correspondence to Minyi Yin  (殷敏毅).

Additional information

Foundation item: the National Natural Science Foundation of China (No. 8167440), the Clinical Research Program of 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine (No. JYLJ026), and the Class IV Peak Subject Program of Shanghai Jiao Tong University School of Medicine (No. GXQ10)

Ethics Approval and Consent to Participate

The study protocol was approved by the Institutional Review Board of Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, and all participants signed a written informed consent form before commencing the study.

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Yang, C., Lu, X., Jiang, W. et al. Application of 3D Digital Reconstruction and Printing to the Diagnosis and Treatment of Iliac Vein Compression. J. Shanghai Jiaotong Univ. (Sci.) 26, 312–318 (2021). https://doi.org/10.1007/s12204-021-2298-0

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  • DOI: https://doi.org/10.1007/s12204-021-2298-0

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