Deformable Registration of Chest Radiographs Using B-spline Based Method with Modified Residual Complexity

  • Zhikang Xiang (相志康)
  • Min Li (李敏)Email author
  • Liang Xiao (肖亮)
  • Zhichao Lian (练智超)
  • Zhihui Wei (韦志辉)


Accurate registration of chest radiographs plays an increasingly important role in medical applications. However, most current intensity-based registration methods rely on the assumption of intensity conservation that is not suitable for alignment of chest radiographs. In this study, we propose a novel algorithm to match chest radiographs, for which the conventional residual complexity (RC) is modified as the similarity measure and the cubic B-spline transformation is adopted for displacement estimation. The modified similarity measure is allowed to incorporate the neighborhood influence into variation of intensity in a justified manner of the weight, while the transformation is implemented with a registration framework of pyramid structure. The results show that the proposed algorithm is more accurate in registration of chest radiographs, compared with some widely used methods such as the sum-of-squared-differences (SSD), correlation coefficient (CC) and mutual information (MI) algorithms, as well as the conventional RC approaches.

Key words

deformable registration chest radiograph residual complexity (RC) B-spline 

CLC number

TP 399 

Document code


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Copyright information

© Shanghai Jiao Tong University and Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Zhikang Xiang (相志康)
    • 1
  • Min Li (李敏)
    • 1
    Email author
  • Liang Xiao (肖亮)
    • 1
  • Zhichao Lian (练智超)
    • 1
  • Zhihui Wei (韦志辉)
    • 1
  1. 1.School of Computer Science and EngineeringNanjing University of Science and TechnologyNanjingChina

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