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Medium chromatic dispersion calculation and correction in spectral-domain optical coherence tomography

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Abstract

A method for determining and correcting distortions in spectral-domain optical coherence tomography images caused by medium dispersion was developed. The method is based on analysis of the phase distribution of the interference signal recorded by an optical coherence tomography device using an iterative approach to find and compensate for the effect of a medium’s chromatic dispersion on point-spread function broadening in optical coherence tomography. This enables compensation of the impact of medium dispersion to an accuracy of a fraction of a radian (units of percent) while avoiding additional measurements and solution of the optimization problem. The robustness of the method was demonstrated experimentally using model and biological objects.

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References

  1. Drexler W, Fujimoto J G. Optical Coherence Tomography Technology and Applications. Berlin: Springer, 2008, 1357

    Book  Google Scholar 

  2. Puliafito C A, Hee M R, Schuman J S, Fujimoto J G. Optical Coherence Tomography of Ocular Diseases. Thorofare, NJ: Slack Inc., 1996, 376

    Google Scholar 

  3. Gupta V, Gupta A, Dogra M R. Atlas of Optical Coherence Tomography of Macular Diseases. Boca Raton: Taylor & Francis, 2004

    Book  Google Scholar 

  4. Zaitsev V Y, Vitkin I A, Matveev L A, Gelikonov VM, Matveyev A L, Gelikonov G V. Recent trends in multimodal optical coherence tomography II. The correlation-stability approach in OCT elastography and methods for visualization of microcirculation. Radiophysics and Quantum Electronics, 2014, 57(3): 210–225

    Article  Google Scholar 

  5. Loduca A L, Zhang C, Zelkha R, Shahidi M. Thickness mapping of retinal layers by spectral-domain optical coherence tomography. American Journal of Ophthalmology, 2010, 150(6): 849–855

    Article  Google Scholar 

  6. Chiu S J, Li X T, Nicholas P, Toth C A, Izatt J A, Farsiu S. Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation. Optics Express, 2010, 18(18): 19413–19428

    Article  Google Scholar 

  7. Fercher A F, Hitzenberger C K, Sticker M, Zawadzki R, Karamata B, Lasser T. Dispersion compensation for optical coherence tomography depth-scan signals by a numerical technique. Optics Communications, 2002, 204(1–6): 67–74

    Article  Google Scholar 

  8. Lippok N, Coen S, Nielsen P, Vanholsbeeck F. Dispersion compensation in Fourier domain optical coherence tomography using the fractional Fourier transform. Optics Express, 2012, 20(21): 23398–23413

    Article  Google Scholar 

  9. Choi W, Baumann B, Swanson E A, Fujimoto J G. Extracting and compensating dispersion mismatch in ultrahigh-resolution Fourier domain OCT imaging of the retina. Optics Express, 2012, 20(23): 25357–25368

    Article  Google Scholar 

  10. Wu X, Gao W. Dispersion analysis in micron resolution spectral domain optical coherence tomography. Journal of the Optical Society of America. B, Optical Physics, 2017, 34(1): 169–177

    Article  MathSciNet  Google Scholar 

  11. Lychagov V V, Ryabukho V P. Chromatic dispersion effects in ultra-low coherence interferometry. Quantum Electronics, 2015, 45(6): 556–560

    Article  Google Scholar 

  12. Yu X, Liu X, Chen S, Luo Y, Wang X, Liu L. High-resolution extended source optical coherence tomography. Optics Express, 2015, 23(20): 26399–26413

    Article  Google Scholar 

  13. Xu D, Huang Y, Kang J U. Graphics processing unit-accelerated real-time compressive sensing spectral domain optical coherence tomography. In: Proceedings of SPIE. 2015, 93301B

    Google Scholar 

  14. Bian H, Gao W. Wavelet transform-based method of compensating dispersion for high resolution imaging in SDOCT. In: Proceedings of SPIE. 2014, 92360X

    Google Scholar 

  15. Pan L, Wang X, Li Z, Zhang X, Bu Y, Nan N, Chen Y, Wang X, Dai F. Depth-dependent dispersion compensation for full-depth OCT image. Optics Express, 2017, 25(9): 10345–10354

    Article  Google Scholar 

  16. Wang B, Jiang Z, Hu Y, Wang Z. A segmental dispersion compensation method to improve axial resolution of specified layer in FD-OCT. In: Proceedings of SPIE, Optical Measurement Technology and Instrumentation. 2016, 101553L

    Google Scholar 

  17. Okano M, Okamoto R, Tanaka A, Ishida S, Nishizawa N, Takeuchi S. Dispersion cancellation in high-resolution two-photon interference. Physical Review A, 2013, 88(4): 043845

    Article  Google Scholar 

  18. Shirai T. Modifications of intensity-interferometric spectral-domain optical coherence tomography with dispersion cancellation. Journal of Optics, 2015, 17(4): 045605

    Article  Google Scholar 

  19. Photiou C, Bousi E, Zouvani I, Pitris C. Using speckle to measure tissue dispersion in optical coherence tomography. Biomedical Optics Express, 2017, 8(5): 2528–2535

    Article  Google Scholar 

  20. Photiou C., Pitris C. Tissue dispersion measurement techniques using optical coherence tomography. In: Proceedings of SPIE, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI. 2017, 100532W

    Google Scholar 

  21. Banaszek K, Radunsky A S, Walmsley I A. Blind dispersion compensation for optical coherence tomography. In: Proceedings of Conference on Lasers and Electro-Optics/International Quantum Electronics Conference and Photonic Applications Systems Technologies, San Francisco, California. 2004, CWJ6

    Google Scholar 

  22. Banaszek K, Radunsky A S, Walmsley I A. Blind dispersion compensation for optical coherence tomography. Optics Communications, 2007, 269(1): 152–155

    Article  Google Scholar 

  23. Matkivsky V A, Moiseev A A, Gelikonov G V, Shabanov D V, Shilyagin P A, Gelikonov V M. Correction of aberrations in digital holography using the phase gradient autofocus technique. Laser Physics Letters, 2016, 13(3): 035601

    Article  Google Scholar 

  24. Leitgeb R A, Wojtkowski M. Complex and coherence noise free Fourier domain optical coherence tomography. In: Drexler W, Fujimoto J G, eds. Optical Coherence Tomography: Technology and Applications. Berlin: Springer, 2008, 177–207

    Chapter  Google Scholar 

  25. Gelikonov V M, Gelikonov G V, Kasatkina I V, Terpelov D A, Shilyagin P A. Coherent noise compensation in spectral-domain optical coherence tomography. Optics and Spectroscopy, 2009, 106(6): 895–900

    Article  Google Scholar 

  26. Fercher A F. Optical coherence tomography. Journal of Biomedical Optics, 1996, 1(2): 157–173

    Article  Google Scholar 

  27. Welge W A, Barton J K. Expanding functionality of commercial optical coherence tomography systems by integrating a custom endoscope. PLoS One, 2015, 10(9): e0139396

    Article  Google Scholar 

  28. Schott Optical glass datasheet (Electronic document) https://refractiveindex.info/download/data/2015/schott-optical-glass-collection-datasheets-july-2015-us.pdf

  29. Batovrin V K, Garmash I A, Gelikonov V M, Gelikonov G V, Lyubarskiǐ A V, Plyavenek A G, Safin S A, Semenov A T, Shidlovskiǐ V R, Shramenko M V, Yakubovich S D. Superluminescent diodes based on single-quantum-well (GaAl)As heterostructures. Quantum Electronics, 1996, 26(2): 109–114

    Article  Google Scholar 

  30. Matveev L A, Zaitsev V Y, Gelikonov G V, Matveyev A L, Moiseev A A, Ksenofontov S Y, Gelikonov V M, Sirotkina M A, Gladkova N D, Demidov V, Vitkin A. Hybrid M-mode-like OCT imaging of three-dimensional microvasculature in vivo using reference-free processing of complex valued B-scans. Optics Letters, 2015, 40(7): 1472–1475

    Article  Google Scholar 

Download references

Acknowledgements

The research in part of the development of the method was supported by the Russian Foundation for Basic Research (Grant No. 15-29-03897). The experimental verification part was supported by the State task for IAP RAS project No. 0035-2014-0018.

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Authors and Affiliations

  1. Institute of Applied Physics, Russian Academy of Sciences, Nizhny Novgorod, 603950, Russia

    Vasily A. Matkivsky, Alexander A. Moiseev, Sergey Yu. Ksenofontov, Irina V. Kasatkina, Grigory V. Gelikonov, Dmitry V. Shabanov, Pavel A. Shilyagin & Valentine M. Gelikonov

Authors
  1. Vasily A. Matkivsky
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  2. Alexander A. Moiseev
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  3. Sergey Yu. Ksenofontov
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  4. Irina V. Kasatkina
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  5. Grigory V. Gelikonov
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  6. Dmitry V. Shabanov
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  7. Pavel A. Shilyagin
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  8. Valentine M. Gelikonov
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Corresponding author

Correspondence to Vasily A. Matkivsky.

Additional information

Vasily A. Matkivsky recived his M.S. degree from Lobachevsky State University of Nizhni Novgorod in 2012. His scientific interests are digital holography, full field and spectral domain OCT, and aberration compensation. His current work is aberration compensation in full field OCT.

Alexander A. Moiseev, Ph.D., recieved his Master degree in Physics in 2008 from Advanced School of General and Applied Physics of Nizny Novgorod State University. He recieved his Ph.D. degree in Radiophysics in 2014 from Institute of the Applied Physics of the Russan Academy of Sciences. His scientific interests are optical coherence tomography system and applications development, signal processing and image enhancement.

Sergey Yu. Ksenofontov, Ph.D., graduated from Nizhny Novgorod University in 1993. He recieved his Ph.D. degree in Environment Monitoring Devices since 2017. His research interests are optical measurement techniques, optical coherence tomography, computationally efficient algorithms. His current work is optical solutions for optical coherence tomography.

Irina V. Kasatkina received her B.S., M. S., and Ph.D. degrees from the Lobachevsky State University of Nizhni Novgorod, Russia in 2000, 2002, and 2005, respectively, all in Radiophysics. She is currently working in the Institute of Applied Physics of the Russian Academy of Sciences. Her scientific interests are nonlinear optics, optical materials, coherent optics and optical tomography.

Grigory V. Gelikonov, Ph.D., graduated from Nizhny Novgorod University in 1992. He recieved his Ph.D. degree in Radiophysics since 2007. His research interests are developing and creation of single mode fiber elements, laboratory and clinical imaging of animal and human tissues, experimental study of middle-infrared laser ablation of biotissue with OCT monitoring, development of improved OCT technique, including cross-polarization OCT and two-wavelength OCT. His current work is multymodal optical coherence tomography, clinical OCT approaches.

Dmitry V. Shabanov, Ph.D., graduated from Nizhny Novgorod University in 1992. He recieved his Ph.D. degree in Radiophysics since 2011. His research interests are optical measurement techniques, optical digital holography, electronics, computer modeling. His current work is optical solutions for optical coherence tomography.

Pavel A. Shilyagin, Ph.D., graduated from Nizhny Novgorod University in 2005, master of Radiophysics. He recieved his Ph.D. degree in Radiophysics since 2009. His research interests are optical measurement techniques, optical coherence tomography, optical instrumentation, medical physics. His current work is optical solutions for optical coherence tomography.

Valentin M.Gelikonov, Ph.D., D.Sc., currently work at Federal State Budgetary Institution of Science, Institute of Applied Physics of the Russian Academy of Sciences (IAP RAS). He is Head of department “Nanoopics and high precision optical measurements”. He graduated from Nizhny Novgorod University in 1966, engineer with “Radiophysics and electronics” specialization. His scientific degrees: 1985–Ph.D., 2007–D.Sc., he won State Prize of Russian Federation in Science and Technology in 1999. His research interests are natural fluctuations of gas laser, nonlinear laser spectroscopy, fiber-optical interferometry, high precision optical measurements, bioimaging. His current work is polarization effects in optical coherence tomography, multymodal optical coherence tomography.

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Matkivsky, V.A., Moiseev, A.A., Ksenofontov, S.Y. et al. Medium chromatic dispersion calculation and correction in spectral-domain optical coherence tomography. Front. Optoelectron. 10, 323–328 (2017). https://doi.org/10.1007/s12200-017-0736-2

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  • DOI: https://doi.org/10.1007/s12200-017-0736-2

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