Frontiers of Optoelectronics in China

, Volume 2, Issue 1, pp 1–8 | Cite as

Homeostatic photobiomodulation

  • Timon Chengyi LiuEmail author
  • Ruochun Liu
  • Ling Zhu
  • Jianqin Yuan
  • Min Hu
  • Songhao Liu
Review Article


Photobiomodulation (PBM) is a modulation of laser irradiation or monochromatic light (LI) on biosystems, which stimulates or inhibits biological functions but does not result in irreducible damage. LI might be of low intensity LI (LIL) (about 10 mW/cm2), or moderate intensity LI (MIL) (102-103 mW/cm2). PBM of LIL or MIL (LPBM or MPBM) is studied from the homeostatic viewpoint in this paper. Homeostasis is rede.ned as the function-specific homeostasis (FSH), a negative-feedback response of a biosystem which maintains the function-specific conditions inside it. PBM is classified into two kinds, the FSH-specific PBM (fPBM) and developmental PBM (dPBM). For fPBM, there is no PBM of LI on the function in FSH, but there is PBM of LI on the function far from FSH. dPBM can disrupt FSH. It can be found that LPBM is an fPBM, and whether MPBM is fPBM or dPBM depends on MIL dose and cell sensitivity. Low level LI therapy is just clinical applications of fPBM, so that it is a cellular rehabilitation.


laser homeostasis rehabilitation photobiomodulation (PBM) phototherapy 


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Copyright information

© Higher Education Press and Springer-Verlag GmbH 2009

Authors and Affiliations

  • Timon Chengyi Liu
    • 1
    • 2
    Email author
  • Ruochun Liu
    • 2
  • Ling Zhu
    • 1
  • Jianqin Yuan
    • 1
  • Min Hu
    • 3
  • Songhao Liu
    • 4
  1. 1.Laboratory of Laser Sports MedicineCollege of Sports Science, South China Normal UniversityGuangzhouChina
  2. 2.College of LifeSouth China Normal UniversityGuangzhouChina
  3. 3.Laboratory Center for Sport Science and MedicineGuangzhou Institute of Physical EducationGuangzhouChina
  4. 4.School for Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhouChina

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