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Evaluation of bone mineral density and 25-hydroxyvitamin D levels in subjects with silica exposure

  • Mustafa Turgut YıldızgörenEmail author
  • Türkan Nadir Öziş
  • Ali Erdem Baki
  • Engin Tutkun
  • Hınç Yılmaz
  • Tülay Tiftik
  • Timur Ekiz
  • Neşe Özgirgin
Regular Article

Abstract

Objective

The purpose of the study was to evaluate the bone mineral density (BMD) and 25-hydroxyvitamin D (25(OH)D) levels in patients with silica exposure.

Materials and methods

The study included 104 male subjects with silica exposure and 36 healthy subjects. Posterior–anterior radiographs were classified according to the International Labour Office (ILO) Classification. Category 0 patients were classified as Group I (n = 54), category I patients were classified as Group II (n = 25), Category II and III patients were classified as Group III (n = 25).

Results

Femoral neck BMD values were significantly lower in Group III (p = 0.007). Lumbar vertebrae BMD values were significantly lower in all groups with silica exposure than in the control group (p = 0.000). The osteoporosis rate was significantly higher in Group III (p = 0.000). Subjects with silica exposure were determined to have diminished 25(OH)D levels (p = 0.012).

Conclusion

The results of this study demonstrated that subjects with silica exposure have diminished BMD and 25(OH)D levels.

Keywords

Silicosis Bone mineral density Osteoporosis Pneumoconiosis Vitamin D 

Notes

Acknowledgements

No funding was received for this article.

Compliance with ethical standards

Conflict of interest

None.

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Copyright information

© The Japanese Society for Hygiene 2016

Authors and Affiliations

  • Mustafa Turgut Yıldızgören
    • 1
    Email author
  • Türkan Nadir Öziş
    • 2
  • Ali Erdem Baki
    • 1
  • Engin Tutkun
    • 3
  • Hınç Yılmaz
    • 3
  • Tülay Tiftik
    • 4
  • Timur Ekiz
    • 4
  • Neşe Özgirgin
    • 4
  1. 1.Department of Physical Medicine and RehabilitationAnkara Occupational Diseases HospitalAnkaraTurkey
  2. 2.Department of Chest DiseasesAnkara Occupational Diseases HospitalAnkaraTurkey
  3. 3.Department of ToxicologyAnkara Occupational Diseases HospitalAnkaraTurkey
  4. 4.Department of Physical Medicine and RehabilitationAnkara Physical Medicine and Rehabilitation Training and Research HospitalAnkaraTurkey

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