Skip to main content
SpringerLink
Log in

Translating Mechanobiology to the Clinic: A Panel Discussion from the 2018 CMBE Conference

  • Commentary
  • Published:
Cellular and Molecular Bioengineering Aims and scope Submit manuscript

A Correction to this article was published on 08 October 2018

This article has been updated

Abstract

The 2018 BMES Cellular and Molecular Bioengineering (CMBE) Conference was organized around the theme of Discovering the Keys: Transformative and Translational Mechanobiology. The conference programming included a panel discussion on Translating Mechanobiology to the Clinic. The goal of the panel was to initiate a dialogue and share pearls of wisdom from participants’ successes and failures in academia and in industry toward translating scientific discoveries in mechanobiology to technology products in the market or toward devices or drugs that impact clinical care. This commentary reviews the major themes and questions discussed during the panel, including defining translational research and how it applies to mechanobiology, the current landscape in translational mechanobiology, the process for translating mechanobiology research, challenges in translating mechanobiology research, and unique opportunities in translating mechanobiology research.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Change history

  • 08 October 2018

    The authors would like to add the following acknowledgment to their article.

References

  1. Austin, C. P. Translating translation. Nat Rev Drug Discov 17(7):455–456, 2018.

    Article  Google Scholar 

  2. Chien, S., et al. Engineering as a new frontier for translational medicine. Sci Transl Med 7(281):281fs13, 2015.

    Article  Google Scholar 

  3. Feng, J., et al. Substrate stiffness influences the outcome of antitumor drug screening in vitro. Clin Hemorheol Microcirc 55(1):121–131, 2013.

    MathSciNet  Google Scholar 

  4. Marcolongo, M. Academic Entrepreneurship: How to Bring Your Scientific Discovery to a Successful Commercial Product. Hoboken, NJ: Wiley, 2017.

    Book  Google Scholar 

  5. Perez-Terzic, C., and M. K. Childers. Regenerative rehabilitation: a new future? Am J Phys Med Rehabil 93(11 Suppl 3):S73–S78, 2014.

    Article  Google Scholar 

  6. Pober, J. S., C. S. Neuhauser, and J. M. Pober. Obstacles facing translational research in academic medical centers. FASEB J 15(13):2303–2313, 2001.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Drexel University, Philadelphia, PA, USA

    Alisa Morss Clyne & Michele Marcolongo

  2. Brown University, Providence, RI, USA

    Eric M. Darling

  3. Columbia University, New York, NY, USA

    Nadeen O. Chahine

Authors
  1. Alisa Morss Clyne
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Michele Marcolongo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Eric M. Darling
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nadeen O. Chahine
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alisa Morss Clyne.

Additional information

Associate Editor Michael R. King oversaw the review of this article.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Clyne, A.M., Marcolongo, M., Darling, E.M. et al. Translating Mechanobiology to the Clinic: A Panel Discussion from the 2018 CMBE Conference. Cel. Mol. Bioeng. 11, 531–535 (2018). https://doi.org/10.1007/s12195-018-0556-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12195-018-0556-5

Keywords

Search

Navigation