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Knowledge-based model building for treatment planning for prostate cancer using commercial treatment planning quality assurance software tools

  • Clinical Technique
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Abstract

This study devised a method to efficiently launch the RapidPlan model for volumetric-modulated arc therapy for prostate cancer in small- and medium-sized facilities using high-quality treatment plans with the PlanIQ software as a reference. Treatment plans were generated for 30 patients with prostate cancer to construct the RapidPlan model using PlanIQ as a reference. In the context of PlanIQ-referenced treatment planning, treatment plans were developed, such that the feasibility dose–volume histogram of each organ-at-risk fell within F ≤ 0.1. For validation of the RapidPlan model, treatment plans were formulated for 20 patients using both RapidPlan and PlanIQ, and the differences were evaluated. The results of RapidPlan model validity assessment revealed that the RapidPlan-produced treatment plans exhibited higher quality in 11 of 20 patients. No significant differences were found between the treatment plans. In conclusion, high-quality treatment plans formulated using PlanIQ as reference facilitated efficient implementation of RapidPlan modeling.

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Data availability

The data in this study are stored in our laboratory and will be shared upon request to the corresponding author.

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Acknowledgements

The authors would like to thank Editage (www.editage.jp) for English language editing.

Funding

This work was supported in part by the Foundation for Promotion of Cancer Research (2022 General Proposal B).

Author information

Authors and Affiliations

  1. Medical Research Institute Kitano Hospital, PIIF Tazuke-kofukai, Osaka, Osaka, 530-8480, Japan

    Nagi Masumoto

  2. Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima, Tokushima, 770-8503, Japan

    Motoharu Sasaki, Yuki Kanazawa & Hitoshi Ikushima

  3. Toyo Medic Co., Ltd, Shinjyukuku, Tokyo, 162-0813, Japan

    Yuji Nakaguchi

  4. Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan

    Takeshi Kamomae

Authors
  1. Nagi Masumoto
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  2. Motoharu Sasaki
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  3. Yuji Nakaguchi
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  4. Takeshi Kamomae
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  5. Yuki Kanazawa
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  6. Hitoshi Ikushima
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Corresponding author

Correspondence to Motoharu Sasaki.

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Conflict of interest

Yuji Nakaguchi is an employee of Toyo Medic Co., Ltd.

Ethical approval

All procedures performed in this study were conducted in accordance with the ethical standards of the Institutional Review Board (IRB) and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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The patients provided informed consent authorizing the use of their personal information for research purposes.

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Masumoto, N., Sasaki, M., Nakaguchi, Y. et al. Knowledge-based model building for treatment planning for prostate cancer using commercial treatment planning quality assurance software tools. Radiol Phys Technol 17, 337–345 (2024). https://doi.org/10.1007/s12194-023-00759-6

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  • DOI: https://doi.org/10.1007/s12194-023-00759-6

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