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Radiological Physics and Technology

, Volume 11, Issue 4, pp 415–422 | Cite as

Accurate and robust systolic myocardial T1 mapping using saturation recovery with individualized delay time: comparison with diastolic T1 mapping

  • Hideo AraiEmail author
  • Masateru Kawakubo
  • Kenichi Sanui
  • Hiroshi Nishimura
  • Toshiaki Kadokami
Article
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Abstract

T1 mapping data are generally acquired in patients’ diastolic phase, wherein their myocardium is the thinnest in the cardiac cycle. However, the analysis of the thin myocardium may cause errors in image registrations and settings related to the region of interest. In this study, we validated systolic T1 mapping using the saturation recovery with individualized delay time (SR-IDT) method and compared it with conventional diastolic T1 mapping. Both diastolic and systolic T1 mappings were performed in the mid-ventricular plane in 10 healthy volunteers (35 ± 9 years, 9 males) and 29 consecutive patients with cardiac diseases (68 ± 14 years, 19 males). Comparison of the myocardial T1 value at diastole and systole was performed with both the Pearson correlation coefficient (r) and the Bland–Altman analysis. Additionally, the systolic myocardial T1 value was compared between the volunteers and patients by using Tukey’s test. Pearson correlation analysis demonstrated a strong positive correlation between diastolic and systolic T1 values (r = 0.88, P < 0.001). The Bland–Altman plot suggested that left ventricular T1 values in the diastole and systole showed high agreement (mean difference and 95% limits of agreement = 17 ± 104 ms). Further, systolic T1 values with SR-IDT in patients in the late gadolinium enhancement (LGE) group were significantly higher than those in the control group (1585 ± 118 ms vs 1469 ± 69 ms; P = 0.024). Therefore, the proposed systolic T1 mapping with the SR-IDT, which was validated with respect to the conventional diastolic method, is a useful clinical tool for the quantitative characterization of the myocardium.

Keywords

T1 mapping Myocardium Systole Saturation recovery Cardiovascular magnetic resonance imaging 
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Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Statement of human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Institutional Review Board (IRB) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies performed with animals.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Japanese Society of Radiological Technology and Japan Society of Medical Physics 2018

Authors and Affiliations

  • Hideo Arai
    • 1
    Email author
  • Masateru Kawakubo
    • 2
  • Kenichi Sanui
    • 1
  • Hiroshi Nishimura
    • 1
  • Toshiaki Kadokami
    • 1
  1. 1.Fukuokaken Saiseikai Futsukaichi HospitalFukuokaJapan
  2. 2.Department of Health Sciences, Faculty of Medical SciencesKyushu UniversityFukuokaJapan

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