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Effectiveness of temporal and dynamic subtraction images of the liver for detection of small HCC on abdominal CT images: comparison of 3D nonlinear image-warping and 3D global-matching techniques

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Abstract

Misregistration errors occur at the periphery of the hepatic region due to respiratory- and interval-related changes in hepatic shape. To reduce these misregistration errors, we developed a temporal and dynamic subtraction technique to enhance small hepatocellular carcinoma (HCC) by using a 3D nonlinear image-warping technique. The study population consisted of 21 patients with HCC. We registered the present and previous arterial-phase CT images or the present nonenhanced and arterial-phase CT images obtained in the same position by 3D global-matching plus 3D nonlinear image-warping. Temporal subtraction images were obtained by subtraction of the previous arterial-phase CT image from the warped present arterial-phase CT image. Dynamic subtraction images were obtained by subtraction of the present nonenhanced CT image from the warped present arterial-phase CT image. When we used this new technique, the number of good or excellent cases increased from 14.2% (3/21 cases) to 71.4% (15/21 cases) on temporal subtraction images. With this technique, subjective rating scores for image quality improved in 57.1% of cases (12/21 cases) on temporal subtraction images and 81.0% of cases (17/21 cases) on dynamic subtraction images. The results indicated that the new subtraction images were greatly improved by use of the 3D nonlinear image-warping technique.

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Authors and Affiliations

  1. Department of Medical Radiological Technology, Kagoshima Medical Technology College, 5417-1 Hirakawa, Kagoshima, 891-0133, Japan

    Eiichiro Okumura

  2. Department of Radiological Technology, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan

    Shigeru Sanada, Masayuki Suzuki, Akihiro Takemura & Osamu Matsui

Authors
  1. Eiichiro Okumura
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  2. Shigeru Sanada
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  3. Masayuki Suzuki
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  4. Akihiro Takemura
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  5. Osamu Matsui
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Correspondence to Eiichiro Okumura.

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Okumura, E., Sanada, S., Suzuki, M. et al. Effectiveness of temporal and dynamic subtraction images of the liver for detection of small HCC on abdominal CT images: comparison of 3D nonlinear image-warping and 3D global-matching techniques. Radiol Phys Technol 4, 109–120 (2011). https://doi.org/10.1007/s12194-010-0110-1

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  • DOI: https://doi.org/10.1007/s12194-010-0110-1

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