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Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis

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Abstract

A voxel-based specific regional analysis system for Alzheimer’s disease (VSRAD) was used for quantitative analysis of parahippocampal atropy with 1.5-tesla (T) MRI in a voxel-wise manner. The analysis of images acquired under a different imaging condition provides an error factor that has a calculated value. Clinical application of 3T-MRI is necessary for establishing a normal data base (N-DB) specific for 3T-MRI data, which permits appropriate application of VSRAD. We established an N-DB specific for 3T-MRI for use in VSRAD. The “Z-score of the parahippocampal gyrus” was 0.79 ± 0.32, and the N-DB of each age group did not have a big deflection when we analyzed a group of physically unimpaired persons in an N-DB specific for 3T-MRI. Therefore, we were able to confirm the validity of the customized N-DB. The “Z-score of the parahippocampal gyrus” was 1.62 ± 0.47 for the N-DB of VSRAD. The numerical value was high for the group of physically unimpaired persons.

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Authors and Affiliations

  1. Department of Radiological Technology, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Masami Goto, Yuuichi Suzuki, Yasushi Watanabe, Yoshirou Satake, Kenji Ino, Keiichi Yano, Kyouhito Iida & Kazuo Mima

  2. Department of Radiology, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Osamu Abe, Naoto Hayashi, Shigeki Aoki, Harushi Mori, Tomohiko Masumoto & Kuni Ohtomo

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  1. Masami Goto
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  2. Yuuichi Suzuki
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  3. Osamu Abe
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  4. Naoto Hayashi
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  5. Shigeki Aoki
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  6. Harushi Mori
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  7. Tomohiko Masumoto
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  8. Yasushi Watanabe
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  9. Yoshirou Satake
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  10. Kenji Ino
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  11. Keiichi Yano
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  13. Kazuo Mima
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  14. Kuni Ohtomo
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Corresponding author

Correspondence to Masami Goto.

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Goto, M., Suzuki, Y., Abe, O. et al. Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis. Radiol Phys Technol 1, 196–200 (2008). https://doi.org/10.1007/s12194-008-0027-0

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  • DOI: https://doi.org/10.1007/s12194-008-0027-0

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