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A role for peripherally inserted central venous catheters in the prevention of catheter-related blood stream infections in patients with hematological malignancies

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Abstract

Central venous catheter-related blood stream infections (CR-BSIs) are a serious complication in patients with hematological malignancies. However, it remains unclear whether there is a difference in the rate of CR-BSI associated with the conventional type of central venous catheters (cCVCs) and peripherally inserted CVCs (PICCs) in such patients. To address this question, we retrospectively investigated the incidence of CR-BSIs associated with PICCs versus cCVCs in patients with hematological malignancies. We used PICCs in all consecutive patients requiring CVC placement between February 2009 and February 2013. We compared the CR-BSI rate in patients with PICCs with that in patients with cCVCs treated between September 2006 and January 2009 (control group). Eighty-four patients received PICCs and 85 received cCVCs. The most common reason for removal due to catheter-related complications was CR-BSI. The CR-BSI rate in the PICC group was significantly lower than that in the cCVC group (PICCs: 1.23/1000 catheter days; cCVCs: 5.30/1000 catheter days; P < 0.01). Catheter-related complications other than CR-BSIs occurred at an extremely low rate in the PICC group. The median catheter-related complication-free survival duration was significantly longer in the PICC group than in the cCVC group. Our study shows that PICCs are useful in patients with hematological malignancies.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Hematology and Oncology, Asahikawa Red Cross Hospital, 1-1 Akebono-cho, Asahikawa, Hokkaido, Japan

    Toshiro Sakai, Kyuhei Kohda & Yuichi Konuma

  2. Department of Infection Control and Prevention, Asahikawa Red Cross Hospital, Asahikawa, Japan

    Yasuko Hiraoka & Yukari Ichikawa

  3. Department of Medical Oncology and Hematology, Sapporo Medical University, Sapporo, Japan

    Kaoru Ono, Hiroto Horiguchi, Ayumi Tatekoshi, Kouichi Takada, Satoshi Iyama & Junji Kato

Authors
  1. Toshiro Sakai
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  2. Kyuhei Kohda
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  3. Yuichi Konuma
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  4. Yasuko Hiraoka
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  5. Yukari Ichikawa
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  6. Kaoru Ono
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  7. Hiroto Horiguchi
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  8. Ayumi Tatekoshi
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  9. Kouichi Takada
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  10. Satoshi Iyama
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  11. Junji Kato
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Correspondence to Toshiro Sakai.

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Sakai, T., Kohda, K., Konuma, Y. et al. A role for peripherally inserted central venous catheters in the prevention of catheter-related blood stream infections in patients with hematological malignancies. Int J Hematol 100, 592–598 (2014). https://doi.org/10.1007/s12185-014-1677-9

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  • DOI: https://doi.org/10.1007/s12185-014-1677-9

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