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Primary mantle-cell non-Hodgkin’s lymphoma of the tongue

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Abstract

The evaluation of tongue swellings often represents a diagnostic challenge, because of the wide spectrum of benign and malignant possible lesions. We report a case of a patient presenting a tongue mass. An incisional biopsy was performed. Diagnosis of primary Mantle Cell non-Hodgkin’s Lymphoma of the tongue was made by histological, immunohistochemical and cytogenetic studies. Our patient was treated with Rituximab–Cyclophosphamide, Epirubicine, Vincristine, Prednisone polychemotherapy plus Rituximab as single agent maintenance. Complete remission was achieved and no relapse has occurred during a follow-up of 53 months. We emphasize the importance of including also NHL in differential diagnosis of a tongue mass.

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Authors and Affiliations

  1. Department of Haematology, Transfusion Medicine and Transplant Immunology, Second University of Naples, Naples, Italy

    Salvatore Guastafierro, Umberto Falcone & Maria Celentano

  2. Department of Radiology, Second University of Naples, Naples, Italy

    Salvatore Cappabianca

  3. Department of Head and Neck Surgery, Second University of Naples, Naples, Italy

    Amerigo Giudice & Giuseppe Colella

  4. Via Unità Italiana 52, 81100, Caserta, Italy

    Umberto Falcone

Authors
  1. Salvatore Guastafierro
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  2. Umberto Falcone
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  3. Maria Celentano
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  4. Salvatore Cappabianca
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  5. Amerigo Giudice
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  6. Giuseppe Colella
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Corresponding author

Correspondence to Umberto Falcone.

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Guastafierro, S., Falcone, U., Celentano, M. et al. Primary mantle-cell non-Hodgkin’s lymphoma of the tongue. Int J Hematol 88, 206–208 (2008). https://doi.org/10.1007/s12185-008-0142-z

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  • DOI: https://doi.org/10.1007/s12185-008-0142-z

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