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Kontrastmittelinduzierte akute Nierenschädigung – Konsensuspapier der Arbeitsgemeinschaft „Herz – Niere“ der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. und der Deutschen Gesellschaft für Nephrologie e. V.

Contrast medium-induced acute kidney injury—Consensus paper of the working group “Heart and Kidney” of the German Cardiac Society and the German Society of Nephrology

  • Konsensuspapiere
  • Published:
Der Kardiologe Aims and scope

Zusammenfassung

Dieses Konsensuspapier ist eine Stellungnahme der Arbeitsgemeinschaft „Herz – Niere“ der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. und der Deutschen Gesellschaft für Nephrologie e. V. zum Thema kontrastmittelinduzierte akute Nierenschädigung. Potenziell nierenschädigendes jodhaltiges Kontrastmittel wird in der interventionellen Medizin und der Computertomographiediagnostik häufig eingesetzt. Eine akute Nierenschädigung tritt bei etwa 8–17 % der Patienten auf. Es werden Risikofaktoren und die zugrunde liegende Pathogenese diskutiert und Empfehlungen zur Prophylaxe und Therapie kontrastmittelinduzierter akuter Nierenschädigungen vorgestellt.

Abstract

This consensus paper summarizes the expert consensus and recommendations of the working group “Heart and Kidney” of the German Cardiac Society (DGK) and the German Society of Nephrology (DGfN) on contrast medium-induced acute kidney injury. Potentially nephrotoxic contrast agents containing iodine are frequently used in interventional medicine and for computer tomography diagnostics. Acute kidney injury occurs in approximately 8–17% of patients exposed to contrast media. The risk factors and underlying pathophysiology are discussed and recommendations for the prophylaxis and treatment of contrast medium-induced acute nephropathy are presented.

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Authors and Affiliations

  1. Klinik für Nieren‑, Hochdruck- und Autoimmunerkrankungen, Klinikum der Landeshauptstadt Stuttgart, Stuttgart, Deutschland

    J. Latus & V. Schwenger

  2. Zentrum für Nieren‑, Hochdruck- und Stoffwechselerkrankungen, Hannover, Deutschland

    G. Schlieper

  3. Klinik für Kardiologie I: Koronare Herzkrankheit, Herzinsuffizienz und Angiologie, Universitätsklinik Münster, Münster, Deutschland

    H. Reinecke

  4. Klinik für Innere Medizin, Nephrologie und Internistische Intensivmedizin, Universitätsklinikum Marburg, Marburg, Deutschland

    J. Hoyer

  5. Institute of Physiology, Center for Cardiovascular Research, Charité – Universitätsmedizin Berlin, Berlin, Deutschland

    P. B. Persson

  6. Klinik für Kardiologie, Herz- und Gefäßzentrum Bad Bevensen, Bad Bevensen, Deutschland

    B. A. Remppis

  7. Klinik für Innere Medizin III, Kardiologie und Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, IMED, Kirrberger Str. 1, 66421, Homburg/Saar, Deutschland

    F. Mahfoud

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Interessenkonflikt

Felix Mahfoud gibt an, Forschungsunterstützung und Vortragshonorare von Medtronic, Recor, Berlin Chemie und Boehringer Ingelheim erhalten zu haben und durch die Deutsche Forschungsgemeinschaft (SFB-TRR219) unterstützt zu werden. J. Latus, V. Schwenger, G. Schlieper, H. Reinecke, J. Hoyer, P.B. Persson und B.A. Remppis geben an, dass kein Interessenkonflikt besteht.

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Latus, J., Schwenger, V., Schlieper, G. et al. Kontrastmittelinduzierte akute Nierenschädigung – Konsensuspapier der Arbeitsgemeinschaft „Herz – Niere“ der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. und der Deutschen Gesellschaft für Nephrologie e. V.. Kardiologe 14, 494–504 (2020). https://doi.org/10.1007/s12181-020-00411-2

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