Literatur
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE, EMPA-REG OUTCOME Investigators (2015) Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med 373:2117–2128
Inzucchi SE, Zinman B, Wanner C, Ferrari R, Fitchett D, Hantel S, Espadero RM, Woerle HJ, Broedl UL, Johansen OE (2015) SGLT2 inhibitors and cardiovascular risk: proposed pathways and review of ongoing outcome trials. Diab Vasc Dis Res 12:90–100
Cherney DZ, Perkins BA, Soleymanlou N, Har R, Fagan N, Johansen OE, Woerle HJ, von Eynatten M, Broedl UC (2014) The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Cardiovasc Diabetol 13:28
Bakris GL, Molitch M (2014) Microalbuminuria as a risk predictor in diabetes: the continuing saga. Diabetes Care 37:867–875
Roden M, Weng J, Eilbracht J, Delafont B, Kim G, Woerle HJ, Broedl UC (2013) EMPA-TREG MONO trial investigators. Epagiflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, phase trial. Lancet Diabetes Endocrinol 1:208–219
Rosenstock J, Ferrannini E (2015) Euglycemic diabetic Ketoacidosis: a predictable, detectable, and preventable safety concern with SGLT2 inhibitors. Diabetes Care 38:1638
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I. Vardarli und C. Özcelik geben an, dass kein Interessenkonflikt besteht.
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Vardarli, I., Özcelik, C. EMPA-REG-OUTCOME-Studie. Kardiologe 10, 78–80 (2016). https://doi.org/10.1007/s12181-016-0047-7
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DOI: https://doi.org/10.1007/s12181-016-0047-7