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Lateral Ligament Instability: Review of Pathology and Diagnosis

  • Management of Ankle Instability (M Hogan, Section Editor)
  • Published:
Current Reviews in Musculoskeletal Medicine Aims and scope Submit manuscript

Abstract

Purpose of Review

Ankle sprains are a common injury that can lead to chronic lateral ankle instability resulting in pain, poor function, and decreased quality of life. The purpose of this review is to present information regarding injury mechanisms to the lateral ligaments of the ankle and the necessary steps to appropriately diagnose lateral ligament instability.

Recent Findings

The literature demonstrates that history and physical examination is often a reliable method for diagnosis of lateral ankle instability. In addition, imaging modalities are often used as adjuncts for diagnosis, especially when physical exam findings are equivocal.

Summary

In summary, chronic lateral ligament instability of the ankle occurs secondary to failure of the lateral ligamentous complex. A focused physical examination to evaluate the anterior talofibular ligament, calcaneofibular ligament, and posterior talofibular ligament is necessary for diagnosis. Imaging modalities including plain radiographs, stress radiographs, and MRI are helpful for definitive diagnosis and to rule out other pathology.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Pihlajamäki H, Hietaniemi K, Paavola M, Visuri T, Mattila VM. Surgical versus functional treatment for acute ruptures of the lateral ligament complex of the ankle in young men: a randomized controlled trial. J Bone Jt Surg-Am Vol. 2010;92:2367–74.

    Article  Google Scholar 

  2. Golditz T, Steib S, Pfeifer K, Uder M, Gelse K, Janka R, et al. Functional ankle instability as a risk factor for osteoarthritis: using T2-mapping to analyze early cartilage degeneration in the ankle joint of young athletes. Osteoarthr Cartil. 2014;22:1377–85.

    Article  CAS  Google Scholar 

  3. Arnold BL, Wright CJ, Ross SE. Functional ankle instability and health-related quality of life. J Athl Train. 2011;46:634–41.

    Article  Google Scholar 

  4. • Gribble PA, Bleakley CM, Caulfield BM, et al. 2016 consensus statement of the International Ankle Consortium: prevalence, impact and long-term consequences of lateral ankle sprains. Br J Sports Med. 2016;50:1493–5. Demonstrates the burden to the health care system associated with chronic lateral ankle stability.

    Article  Google Scholar 

  5. van den Bekerom MPJ, Oostra RJ, Alvarez PG, van Dijk CN. The anatomy in relation to injury of the lateral collateral ligaments of the ankle: a current concepts review. Clin Anat. 2008;21:619–26.

    Article  Google Scholar 

  6. Clanton TO, Waldrop NE III. Chapter 30 - athletic injuries to the soft tissues of the foot and ankle. In: Coughlin M, Saltzman C (eds) Mann’s surgery of the foot and ankle. Philadelphia: Elsevier Inc.; 2013. pp. 1531–687.

  7. • Kakegawa A, Mori Y, Tsuchiya A, Sumitomo N, Fukushima N, Moriizumi T. Independent attachment of lateral ankle ligaments: anterior talofibular and calcaneofibular ligaments. J Foot Ankle Surg. 2019. https://doi.org/10.1053/j.jfas.2018.12.009. Anatomic study to help characterize ATFL and CFL attachments and the relationship between the two ligaments.

  8. • Herzog MM, Kerr ZY, Marshall SW, Wikstrom EA. Epidemiology of ankle sprains and chronic ankle instability. J Athl Train. 2019. https://doi.org/10.4085/1062-6050-447-17. Demonstrates the high incidence of lateral ankle injuries and prevalence of chronic ankle instability.

  9. Waterman BR, Owens BD, Davey S, Zacchilli MA, Belmont PJ Jr. The epidemiology of ankle sprains in the United States. J Bone Joint Surg Am. 2010;92:2279–84.

    Article  Google Scholar 

  10. Ferran NA, Maffulli N. Epidemiology of sprains of the lateral ankle ligament complex. Foot Ankle Clin. 2006;11:659–62.

    Article  Google Scholar 

  11. • Slater K. Acute lateral ankle instability. Foot Ankle Clin. 2018;23:523–37. Overview of background information, anatomy, diagnosis, and treatment of lateral ankle instability.

    Article  Google Scholar 

  12. Attarian DE, McCrackin HJ, DeVito DP, McElhaney JH, Garrett WE Jr. Biomechanical characteristics of human ankle ligaments. Foot Ankle. 1985;6:54–8.

    Article  CAS  Google Scholar 

  13. • Hunt KJ, Pereira H, Kelley J, Anderson N, Fuld R, Baldini T, et al. The role of calcaneofibular ligament injury in ankle instability: implications for surgical management. Am J Sports Med. 2019;47:431–7. A cadaver study that demonstrates biomechanical changes of the ankle with disruption of the calcaneofibular ligament.

    Article  Google Scholar 

  14. • Porter DA, Kamman KA. Chronic lateral ankle instability. Foot Ankle Clin. 2018;23:539–54. Overview of background information, anatomy, diagnosis, and treatment of chronic lateral ankle instability.

    Article  Google Scholar 

  15. • Hertel J, Corbett RO. An updated model of chronic ankle instability. J Athl Train. 2019. https://doi.org/10.4085/1062-6050-344-18. Explains how pathologic mechanical, sensory, and motor changes contribute to the development of chronic ankle instability.

  16. van Dijk CN, Lim LS, Bossuyt PM, Marti RK. Physical examination is sufficient for the diagnosis of sprained ankles. J Bone Joint Surg (Br). 1996;78:958–62.

    Article  Google Scholar 

  17. Frey C, Bell J, Teresi L, Kerr R, Feder K. A comparison of MRI and clinical examination of acute lateral ankle sprains. Foot Ankle Int. 1996;17:533–7.

    Article  CAS  Google Scholar 

  18. Seligson D, Gassman J, Pope M. Ankle instability: evaluation of the lateral ligaments. Am J Sports Med. 1980;8:39–42.

    Article  CAS  Google Scholar 

  19. • Gribble PA. Evaluating and differentiating ankle instability. J Athl Train. 2019. https://doi.org/10.4085/1062-6050-484-17. Overview of a comprehensive physical exam and imaging modalities that lead to the diagnosis of lateral ligament instability of the ankle.

  20. Polzer H, Kanz KG, Prall WC, Haasters F, Ockert B, Mutschler W, et al. Diagnosis and treatment of acute ankle injuries: development of an evidence-based algorithm. Orthop Rev. 2011;4:5.

    Article  Google Scholar 

  21. Frost SCL, Amendola A. Is stress radiography necessary in the diagnosis of acute or chronic ankle instability? Clin J Sport Med. 1999;9:40–5.

    Article  CAS  Google Scholar 

  22. Chan KW, Ding BC, Mroczek KJ. Acute and chronic lateral ankle instability in the athlete. Bull NYU Hosp Jt Dis. 2011;69:17–26.

    PubMed  Google Scholar 

  23. Stiell IG, Mcknight RD, Greenberg GH, McDowell I, Nair RC, Wells GA, et al. Implementation of the Ottawa Ankle Rules. J Am Med Assoc. 1994;271:827–32.

    Article  CAS  Google Scholar 

  24. Bachmann LM, Kolb E, Koller MT, Steurer J, ter Riet G. Accuracy of Ottawa ankle rules to exclude fractures of the ankle and mid-foot: systematic review. BMJ. 2003;326:417.

    Article  Google Scholar 

  25. Barelds I, Krijnen WP, van de Leur JP, van der Schans CP, Goddard RJ. Diagnostic accuracy of clinical decision rules to exclude fractures in acute ankle injuries: systematic review and meta-analysis. J Emerg Med. 2017;53:353–68.

    Article  Google Scholar 

  26. Perrich KD, Goodwin DW, Hecht PJ, Cheung Y. Ankle ligaments on MRI: appearance of normal and injured ligaments. AJR Am J Roentgenol. 2009;193:687–95.

    Article  Google Scholar 

  27. Rosenberg ZS, Beltran J, Bencardino JT. MR imaging of the ankle and foot. Radiographics. 2000;20:S153–79.

    Article  Google Scholar 

  28. • Salat P, Le V, Veljkovic A, Cresswell ME. Imaging in foot and ankle instability. Foot Ankle Clin. 2018;23:499–522.e28. Overview of the different imaging modalities used to evaluate ankle injuries including use of radiographs, MRI, and ultrasound.

    Article  Google Scholar 

  29. Oae K, Takao M, Uchio Y, Ochi M. Evaluation of anterior talofibular ligament injury with stress radiography, ultrasonography and MR imaging. Skelet Radiol. 2010;39:41–7.

    Article  Google Scholar 

  30. van Dijk CN, Molenaar AH, Cohen RH, Tol JL, Bossuyt PM, Marti RK. Value of arthrography after supination trauma of the ankle. Skelet Radiol. 1998;27:256–61.

    Article  Google Scholar 

  31. Joshy S, Abdulkadir U, Chaganti S, Sullivan B, Hariharan K. Accuracy of MRI scan in the diagnosis of ligamentous and chondral pathology in the ankle. Foot Ankle Surg. 2010;16(2):78–80.

  32. Cha SD, Kim HS, Chung ST, Yoo JH, Park JH, Kim JH, et al. Intra-articular lesions in chronic lateral ankle instability: comparison of arthroscopy with magnetic resonance imaging findings. Clin Orthop Surg. 2012;4:293–9.

    Article  Google Scholar 

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Correspondence to Simon Lee.

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Conflict of Interest

Edward Hur has no conflicts of interest to declare.

Daniel Bohl is a committee member for the American Orthopaedic Foot & Ankle Society and received a research grant from OpEd.

Simon Lee is a board or committee member of the American Orthopaedic Foot & Ankle Society; member of the editorial or governing board of Foot and Ankle International; and receives publishing royalties and financial or material support from SLACK Incorporated.

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No human or animal subjects were used for completion of this article.

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This article is part of the Topical Collection on Management of Ankle Instability

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Hur, E.S., Bohl, D.D. & Lee, S. Lateral Ligament Instability: Review of Pathology and Diagnosis. Curr Rev Musculoskelet Med 13, 494–500 (2020). https://doi.org/10.1007/s12178-020-09641-z

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  • DOI: https://doi.org/10.1007/s12178-020-09641-z

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